Department of Cardiology, Kosuyolu Heart and Research Hospital, Istanbul, Turkey.
Heart Lung. 2010 Mar-Apr;39(2):116-20. doi: 10.1016/j.hrtlng.2009.07.004.
Peripheral artery disease (PAD) is an atherosclerotic disease associated with cardiovascular risk factors, and with high cardiovascular morbidity and mortality. This study sought to assess the prevalence of angiographic coronary artery disease (CAD), and to determine the predictive value of traditional cardiovascular risk factors on the presence of CAD in patients with PAD of the lower extremities.
In total, 231 patients who presented at hospital complaining of intermittent claudication were included. All patients underwent simultaneous peripheral and cardiac angiography. Age, gender, hypertension, diabetes, smoking, and lipid values were recorded.
The coronary angiograms of 64 (28%) patients were within normal limits, and 167 (72%) patients manifested CAD. Logistic regression analysis revealed that hypertension and diabetes were independent predictors for the presence of CAD or PAD.
Aggressive treatment of cardiovascular risk factors, especially hypertension and diabetes, in PAD is critically important in reducing mortality and morbidity.
外周动脉疾病（PAD）是一种与心血管危险因素相关的动脉粥样硬化性疾病，具有较高的心血管发病率和死亡率。本研究旨在评估下肢 PAD 患者中冠状动脉疾病（CAD）的发生率，并确定传统心血管危险因素对 CAD 存在的预测价值。
共纳入 231 例因间歇性跛行就诊的患者。所有患者均接受了外周血管和心脏同时造影。记录年龄、性别、高血压、糖尿病、吸烟和血脂值。
64 例（28%）患者的冠状动脉造影正常，167 例（72%）患者存在 CAD。Logistic 回归分析显示，高血压和糖尿病是 CAD 或 PAD 存在的独立预测因素。
在外周动脉疾病中积极治疗心血管危险因素，尤其是高血压和糖尿病，对于降低死亡率和发病率至关重要。
