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[成人纵隔神经源性肿瘤]

[Neurogenic tumors of the mediastinum in adults].

作者信息

Mordant P, Le Pimpec-Barthes F, Riquet M

机构信息

Service de chirurgie thoracique, hôpital européen Georges-Pompidou, 20 rue Leblanc, 75015 Paris, France.

出版信息

Rev Pneumol Clin. 2010 Feb;66(1):81-94. doi: 10.1016/j.pneumo.2009.12.010. Epub 2010 Feb 19.

Abstract

In adults, mediastinal neurogenic tumours constitute the third group of mediastinal tumours, after thymomas and lymphomas. If the group of neurogenic tumour is frequent, each type of tumour is relatively unusual in everyday's clinic. Among them, nerve sheath tumours are the more frequent, followed by tumour of the autonomic system. Askin tumour remains uncommon. Treatment of this tumour requires complete preoperative work-up, including standard radiography, CT-scan, MRI, and sometimes nuclear imaging. In most cases, the treatment is based on surgical resection, and may be associated with radiotherapy or chemotherapy in case of malignant tumour or incomplete resection. Better understanding of these tumours, including their molecular abnormalities, may lead to new changes in their classifications, and to their management.

摘要

在成人中,纵隔神经源性肿瘤是继胸腺瘤和淋巴瘤之后的第三组纵隔肿瘤。虽然神经源性肿瘤组较为常见,但每种类型的肿瘤在日常临床中相对不常见。其中,神经鞘瘤最为常见,其次是自主神经系统肿瘤。Askin瘤仍然不常见。该肿瘤的治疗需要完善的术前检查,包括标准的X线摄影、CT扫描、MRI,有时还需要核成像。在大多数情况下,治疗以手术切除为主,对于恶性肿瘤或切除不完全的情况,可能需要联合放疗或化疗。对这些肿瘤的深入了解,包括其分子异常,可能会导致其分类和治疗管理的新变化。

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