Ponsford Tipps Ann M, Weidner Noel
Department of Pathology, University of California, San Diego, California, USA.
Diagn Cytopathol. 2012 Oct;40(10):906-11. doi: 10.1002/dc.21650. Epub 2011 Feb 14.
We report a very unusual case of a posterior mediastinal tumor in a young man, which we diagnosed by fine-needle aspiration cytology as most consistent with ganglioneuroma, maturing subtype. The cytopathologic features were interpreted using the classification of neuroblastic tumors as defined by the International Neuroblastoma Pathology Committee. Neuroblastic tumors are peculiar tumors that have capacity for maturation, and hence they present as a spectrum of tumors, ranging from the undifferentiated neuroblastoma, to ganglioneuroblastoma, to the mature version ganglioneuroma. The practicing surgical pathologist or cytopathologist who does not regularly encounter pediatric specimens may experience difficulty interpreting a specimen from one of these tumors. The following case report discusses application of these criteria to cytopathologic diagnosis of these tumors.
我们报告了一例非常罕见的年轻男性后纵隔肿瘤病例，通过细针穿刺细胞学检查，我们诊断其最符合成熟型神经节神经瘤。细胞病理学特征依据国际神经母细胞瘤病理委员会定义的神经母细胞瘤肿瘤分类进行解读。神经母细胞瘤肿瘤是一类特殊的具有成熟能力的肿瘤，因此它们呈现出一系列肿瘤类型，从不分化的神经母细胞瘤，到神经节母细胞瘤，再到成熟型神经节神经瘤。不经常接触儿科标本的外科病理学家或细胞病理学家在解读这些肿瘤的标本时可能会遇到困难。以下病例报告讨论了这些标准在这些肿瘤细胞病理学诊断中的应用。
