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神经鞘瘤中18F-FDG正电子发射断层扫描的假阳性结果——给报告医生的警示

False Positive 18F-FDG Positron Emission Tomography Findings in Schwannoma-A Caution for Reporting Physicians.

作者信息

Boré Paul, Descourt Renaud, Ollivier Luc, Le Roux Pierre-Yves, Abgral Ronan

机构信息

Service d'Oncologie Médicale, Centre Hospitalier Régional et Universitaire de Brest, Université de Bretagne Occidentale, Brest, France.

Service de Radiothérapie, Centre Hospitalier Régional et Universitaire de Brest, Université de Bretagne Occidentale, Brest, France.

出版信息

Front Med (Lausanne). 2018 Oct 8;5:275. doi: 10.3389/fmed.2018.00275. eCollection 2018.

Abstract

Schwannoma is a rare source of false-positive 18F-fluorodeoxyglucose (18F-FDG) uptake in Positron-emission tomography (PET/CT), inducing potential errors in staging of several solid cancer, with implications for patient management. This clinical case reports the situation of a patient undergoing an 18F-FDG-PET/CT for initial staging of an ovarian adenocarcinoma. We found a high paramediastinal hypermetabolic mass suspicious of remote extension or secondary synchronous primitive tumor. The biopsy finally reveals a histopathology of Schwannoma, allowing the patient to be eligible for a surgical procedure of her ovarian adenocarcinoma by rejecting the hypothesis of malignancy.

摘要

神经鞘瘤是正电子发射断层扫描(PET/CT)中18F-氟脱氧葡萄糖(18F-FDG)摄取出现假阳性的罕见原因,可在几种实体癌的分期中导致潜在错误,对患者管理产生影响。本临床病例报告了一名接受18F-FDG-PET/CT检查以对卵巢腺癌进行初始分期的患者的情况。我们发现一个高代谢的纵隔旁肿块,怀疑有远处转移或继发性同步原发性肿瘤。活检最终显示为神经鞘瘤的组织病理学结果,排除了恶性肿瘤的假设,使患者有资格接受卵巢腺癌的手术治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/320e/6186987/4c54655075e5/fmed-05-00275-g0001.jpg

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