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From hematopoietic progenitors to B cells: mechanisms of lineage restriction and commitment.
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Shaping up a lineage--lessons from B lymphopoesis.
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Transcription control of early B cell differentiation.
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Genetic networks that regulate B lymphopoiesis.
Curr Opin Hematol. 2005 May;12(3):203-9. doi: 10.1097/01.moh.0000160735.67596.a0.
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Aryl Hydrocarbon Receptor Activation Suppresses EBF1 and PAX5 and Impairs Human B Lymphopoiesis.
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Pax5 promotes B lymphopoiesis and blocks T cell development by repressing Notch1.
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Ikaros fingers on lymphocyte differentiation.
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The transcriptional regulation of B cell lineage commitment.
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A new pipeline SPICE identifies novel JUN-IKZF1 composite elements.
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The HDAC7-TET2 epigenetic axis is essential during early B lymphocyte development.
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Chromodomain helicase DNA-binding 4 (CHD4) regulates early B cell identity and V(D)J recombination.
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本文引用的文献

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A robust and highly efficient immune cell reprogramming system.
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Epigenetic chromatin states uniquely define the developmental plasticity of murine hematopoietic stem cells.
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A recurrent network involving the transcription factors PU.1 and Gfi1 orchestrates innate and adaptive immune cell fates.
Immunity. 2009 Oct 16;31(4):576-86. doi: 10.1016/j.immuni.2009.07.011. Epub 2009 Oct 8.
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Distinct roles for E12 and E47 in B cell specification and the sequential rearrangement of immunoglobulin light chain loci.
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Genome-wide mapping of HATs and HDACs reveals distinct functions in active and inactive genes.
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Opposing effects of SWI/SNF and Mi-2/NuRD chromatin remodeling complexes on epigenetic reprogramming by EBF and Pax5.
Proc Natl Acad Sci U S A. 2009 Jul 7;106(27):11258-63. doi: 10.1073/pnas.0809485106. Epub 2009 Jun 19.
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Stepwise activation of enhancer and promoter regions of the B cell commitment gene Pax5 in early lymphopoiesis.
Immunity. 2009 Apr 17;30(4):508-20. doi: 10.1016/j.immuni.2009.01.012. Epub 2009 Apr 2.
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Genome-wide lineage-specific transcriptional networks underscore Ikaros-dependent lymphoid priming in hematopoietic stem cells.
Immunity. 2009 Apr 17;30(4):493-507. doi: 10.1016/j.immuni.2009.01.014. Epub 2009 Apr 2.
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E2A proteins maintain the hematopoietic stem cell pool and promote the maturation of myelolymphoid and myeloerythroid progenitors.
Proc Natl Acad Sci U S A. 2009 Feb 10;106(6):1930-5. doi: 10.1073/pnas.0808866106. Epub 2009 Jan 30.

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