• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

慢性胰腺炎的微量营养素治疗:理论依据与影响

Micronutrient therapy for chronic pancreatitis: rationale and impact.

作者信息

Braganza Joan M, Dormandy Thomas L

机构信息

Royal Infirmary, Manchester, United Kingdom.

出版信息

JOP. 2010 Mar 5;11(2):99-112.

PMID:20208316
Abstract

Micronutrient therapy, designed to buttress tissue methyl and thiol groups, curbs attacks and controls background pain in patients with chronic pancreatitis, irrespective of aetiology. This outcome and the premises upon which it is based facilitate an understanding of links with mutations in genes for hereditary pancreatitis and cystic fibrosis, demography, and predisposition to pancreatic cancer. Above all, there is an opportunity for prophylaxis in individuals at high risk of developing the disease.

摘要

旨在增强组织甲基和硫醇基团的微量营养素疗法,可抑制慢性胰腺炎患者的发作并控制背景疼痛,无论其病因如何。这一结果及其所基于的前提有助于理解与遗传性胰腺炎和囊性纤维化基因中的突变、人口统计学以及胰腺癌易感性之间的联系。最重要的是,对于有患该疾病高风险的个体而言,存在预防的机会。

相似文献

1
Micronutrient therapy for chronic pancreatitis: rationale and impact.慢性胰腺炎的微量营养素治疗:理论依据与影响
JOP. 2010 Mar 5;11(2):99-112.
2
Hereditary chronic pancreatitis.遗传性慢性胰腺炎。
Best Pract Res Clin Gastroenterol. 2008;22(1):115-30. doi: 10.1016/j.bpg.2007.10.019.
3
Idiopathic chronic pancreatitis.特发性慢性胰腺炎
Best Pract Res Clin Gastroenterol. 2008;22(1):105-13. doi: 10.1016/j.bpg.2007.10.006.
4
Chronic pancreatitis.慢性胰腺炎。
Lancet. 2011 Apr 2;377(9772):1184-97. doi: 10.1016/S0140-6736(10)61852-1.
5
Hereditary pancreatitis in children: surgical implications with special regard to genetic background.儿童遗传性胰腺炎:特别考虑遗传背景的手术意义。
J Pediatr Surg. 2009 Nov;44(11):2078-82. doi: 10.1016/j.jpedsurg.2009.05.023.
6
Chronic pancreatitis: challenges and advances in pathogenesis, genetics, diagnosis, and therapy.慢性胰腺炎:发病机制、遗传学、诊断及治疗方面的挑战与进展
Gastroenterology. 2007 Apr;132(4):1557-73. doi: 10.1053/j.gastro.2007.03.001.
7
Micronutrient therapy for chronic pancreatitis: premises and pitfalls.
JOP. 2013 Jul 10;14(4):304-8. doi: 10.6092/1590-8577/1580.
8
[Dutch patients with hereditary pancreatitis; high mutation frequency, relatively little pain].[荷兰遗传性胰腺炎患者;突变频率高,疼痛相对较少]
Ned Tijdschr Geneeskd. 2009;153:A324.
9
Risk factors in chronic pancreatitis.
Rom J Intern Med. 2009;47(1):3-8.
10
Folate deficiency in chronic pancreatitis.
JOP. 2010 Jul 5;11(4):409-10; author reply 413-4.

引用本文的文献

1
Steroids as rescue therapy for vitamin A-induced acute liver failure.类固醇作为维生素A诱导的急性肝衰竭的抢救疗法。
BMJ Case Rep. 2020 Mar 4;13(3):e233902. doi: 10.1136/bcr-2019-233902.
2
A phase 1/2 trial to evaluate the pharmacokinetics, safety, and efficacy of NI-03 in patients with chronic pancreatitis: study protocol for a randomized controlled trial on the assessment of camostat treatment in chronic pancreatitis (TACTIC).一项评估 NI-03 在慢性胰腺炎患者中的药代动力学、安全性和疗效的 1/2 期临床试验:一项关于 camostat 治疗慢性胰腺炎评估的随机对照试验(TACTIC)的研究方案。
Trials. 2019 Aug 14;20(1):501. doi: 10.1186/s13063-019-3606-y.
3
Food-Induced Acute Pancreatitis.
食物诱导的急性胰腺炎
Dig Dis Sci. 2017 Dec;62(12):3287-3297. doi: 10.1007/s10620-017-4817-2. Epub 2017 Oct 30.
4
Pathogenic mechanisms of pancreatitis.胰腺炎的发病机制。
World J Gastrointest Pharmacol Ther. 2017 Feb 6;8(1):10-25. doi: 10.4292/wjgpt.v8.i1.10.
5
Antioxidants for pain in chronic pancreatitis.用于慢性胰腺炎疼痛的抗氧化剂。
Cochrane Database Syst Rev. 2014 Aug 21;2014(8):CD008945. doi: 10.1002/14651858.CD008945.pub2.
6
Reappraisal of xenobiotic-induced, oxidative stress-mediated cellular injury in chronic pancreatitis: a systematic review.对慢性胰腺炎中异源物诱导的、氧化应激介导的细胞损伤的重新评估:一项系统综述
World J Gastroenterol. 2014 Mar 21;20(11):3033-43. doi: 10.3748/wjg.v20.i11.3033.
7
Pain in chronic pancreatitis: managing beyond the pancreatic duct.慢性胰腺炎疼痛的处理:超越胰管的思考。
World J Gastroenterol. 2013 Oct 14;19(38):6319-28. doi: 10.3748/wjg.v19.i38.6319.
8
Cytokine profiles in patients receiving antioxidant therapy within the ANTICIPATE trial.在 ANTICIPATE 试验中接受抗氧化治疗的患者的细胞因子谱。
World J Gastroenterol. 2013 Jul 7;19(25):4001-6. doi: 10.3748/wjg.v19.i25.4001.
9
Assessment of oxidative status in chronic pancreatitis and its relation with zinc status.慢性胰腺炎氧化状态的评估及其与锌状态的关系。
Indian J Gastroenterol. 2011 Mar;30(2):84-8. doi: 10.1007/s12664-011-0094-8. Epub 2011 May 20.