Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Ling-Ling Road, Shanghai 200032, China.
Org Lett. 2010 Apr 2;12(7):1444-7. doi: 10.1021/ol100090r.
Difluoromethyl 2-pyridyl sulfone, a previously unknown compound, was found to act as a novel and efficient gem-difluoroolefination reagent for both aldehydes and ketones. It was found that the fluorinated sulfinate intermediate in the reaction is relatively stable, which can be observed by (19)F NMR and trapped with CH(3)I.
二氟甲基 2-吡啶砜，一种以前未知的化合物，被发现可作为醛和酮的新型且有效的偕二氟烯烃化试剂。反应中发现氟化亚砜中间体相对稳定，可通过 (19)F NMR 观察到，并可与 CH(3)I 捕获。
