Nataraja Ramesh M, Bandi Ashwath, Clarke Simon A, Haddad Munther J
Department of Pediatric Surgery, Chelsea and Westminster Hospital NHS Foundation Trust, London, United Kingdom.
J Laparoendosc Adv Surg Tech A. 2010 May;20(4):391-4. doi: 10.1089/lap.2009.0193.
Controversy exists over the association between laparoscopic (LA) and open appendicectomy (OA) and the formation of postoperative intra-abdominal abscesses (IAAs). Our aim was to compare the outcome following these two techniques in a pediatric population.
A retrospective data collection was carried out on all patients undergoing either an LA or OA at a single center over a 26-month period. Patients were identified from a hospital database and theater records. An intra-abdominal abscess was defined as recorded pyrexia, a raised inflammatory marker, and radiologic confirmation of an intra-abdominal collection. Other parameters studied included wound infection, appendiceal perforation, hospital stay, conversion rate, microbiology, histology, radiologic investigation, and serologic analysis. Data were analyzed from using Fisher's exact and Mann-Whitney tests, as appropriate. A P-value of <0.05 was considered significant.
Two hundred children were identified, with a median follow-up of 18 months. Forty patients underwent an LA and 151 an OA. Nine patients underwent interval appendicectomy and were not included in the final data. There was no difference between the two groups in terms of baseline demographics, duration of stay (P = 0.5), or wound infection (P = 1.0). The incidence of an intra-abdominal abscess was 0 of 40 (0%) in the laparoscopic group and 5 of 151 (3.3%) in the open group, although this was not statistically significant (P = 0.8). The median time to postoperative diagnosis of abscess was 9 days (range, 8-11). A consultant was present in more laparoscopic procedures than open (88 versus 24%; P = 0.0001).
The rate of intra-abdominal abscess formation was not significantly different following either an LA or OA, although there were no intra-abdominal abscesses observed in the laparoscopic group. Further investigation could address this finding more accurately in a randomized, controlled trial.
腹腔镜阑尾切除术(LA)与开腹阑尾切除术(OA)和术后腹腔内脓肿(IAA)形成之间的关联存在争议。我们的目的是比较这两种技术在儿科人群中的结果。
对在单一中心26个月期间接受LA或OA的所有患者进行回顾性数据收集。从医院数据库和手术记录中识别患者。腹腔内脓肿定义为记录的发热、炎症标志物升高以及腹腔内积液的影像学证实。研究的其他参数包括伤口感染、阑尾穿孔、住院时间、转换率、微生物学、组织学、影像学检查和血清学分析。数据在适当情况下使用Fisher精确检验和Mann-Whitney检验进行分析。P值<0.05被认为具有统计学意义。
确定了200名儿童,中位随访时间为18个月。40例患者接受了LA,151例接受了OA。9例患者接受了间隔阑尾切除术,未纳入最终数据。两组在基线人口统计学、住院时间(P = 0.5)或伤口感染(P = 1.0)方面没有差异。腹腔镜组腹腔内脓肿的发生率为40例中的0例(0%),开腹组为151例中的5例(3.3%),尽管这在统计学上没有显著差异(P = 0.8)。术后脓肿诊断的中位时间为9天(范围8 - 11天)。与开腹手术相比,更多的腹腔镜手术有顾问在场(88%对24%;P = 0.0001)。
LA或OA后腹腔内脓肿形成率没有显著差异,尽管腹腔镜组未观察到腹腔内脓肿。进一步的研究可以在随机对照试验中更准确地解决这一发现。