Paik P S, Towson J A, Anthone G J, Ortega A E, Simons A J, Beart R W
Department of Surgery, University of Southern California School of Medicine, Los Angeles, CA 90033-4612, USA.
J Gastrointest Surg. 1997 Mar-Apr;1(2):188-92; discussion 192-3. doi: 10.1016/s1091-255x(97)80108-4.
Recent findings in a small number of studies have suggested a trend toward increased infectious complications following laparoscopic appendectomy. The purpose of the present review was to evaluate the incidence of postappendectomy intra-abdominal abscess formation following laparoscopic and open appendectomies. Using the surgical database of the Los Angeles County-University of Southern California Medical Center, we reviewed the records of all appendectomies performed at the center between March 1993 and September 1995. Incidental appendectomies as well as appendectomies in pediatric patients under the age of 18 years were excluded. A total of 2497 appendectomies were identified; indications for these procedures included acute appendicitis in 1422 cases (57%), gangrenous appendicitis in 289 (12%), and perforated appendicitis in 786 (31%). The intraoperative diagnosis made by the surgeon was used for classification. A two-tailed P value of <0.05 was considered significant. There was no significant difference in the rate of abscess formation between the groups undergoing open and laparoscopic appendectomies for acute and gangrenous appendicitis. In patients with perforated appendicitis, a total of 26 postappendectomy intra-abdominal abscesses occurred following 786 appendectomies for an overall abscess formation rate of 3.3%. Eighteen abscesses occurred following 683 open appendectomies (2.6%), six abscesses occurred following 67 laparoscopic appendectomies (9.0%), and the remaining two abscesses occurred following 36 converted cases (5.6%). For perforated appendicitis, however, there was a statistically significant increase in the rate of abscess formation following laparoscopic appendectomy compared to conventional open appendectomy (9.0% vs. 2.6%, P = 0.015). There was no significant difference in the rate of abscess formation between open vs. converted cases or between laparoscopic vs. converted cases. A comparison of the length of the postoperative hospital stay showed no significant difference between open and laparoscopic appendectomy for perforated appendicitis (6.1 days vs. 5.9 days). Laparoscopic appendectomy for perforated appendicitis is associated with a higher rate of postoperative intra-abdominal abscess formation without the benefit of a shortened hospital stay. Given these findings, laparoscopic appendectomy is not recommended in patients with perforated appendicitis.
最近少数研究中的发现表明,腹腔镜阑尾切除术后感染并发症有增加的趋势。本综述的目的是评估腹腔镜阑尾切除术和开腹阑尾切除术后阑尾切除术后腹腔内脓肿形成的发生率。利用洛杉矶县 - 南加州大学医学中心的手术数据库,我们回顾了1993年3月至1995年9月期间该中心进行的所有阑尾切除术的记录。排除了附带阑尾切除术以及18岁以下儿科患者的阑尾切除术。共确定了2497例阑尾切除术;这些手术的适应症包括1422例(57%)急性阑尾炎、289例(12%)坏疽性阑尾炎和786例(31%)穿孔性阑尾炎。外科医生做出的术中诊断用于分类。双侧P值<0.05被认为具有统计学意义。对于急性和坏疽性阑尾炎,开腹阑尾切除术组和腹腔镜阑尾切除术组之间的脓肿形成率没有显著差异。在穿孔性阑尾炎患者中,786例阑尾切除术后共发生26例阑尾切除术后腹腔内脓肿,总体脓肿形成率为3.3%。683例开腹阑尾切除术后发生18例脓肿(2.6%),67例腹腔镜阑尾切除术后发生6例脓肿(9.0%),其余2例脓肿发生在36例中转病例后(5.6%)。然而,对于穿孔性阑尾炎,与传统开腹阑尾切除术相比,腹腔镜阑尾切除术后脓肿形成率有统计学显著增加(9.0%对2.6%,P = 0.015)。开腹与中转病例之间或腹腔镜与中转病例之间的脓肿形成率没有显著差异。对术后住院时间的比较显示,穿孔性阑尾炎的开腹阑尾切除术和腹腔镜阑尾切除术之间没有显著差异(6.1天对5.9天)。穿孔性阑尾炎的腹腔镜阑尾切除术与术后腹腔内脓肿形成率较高相关,且没有缩短住院时间的益处。鉴于这些发现,不建议对穿孔性阑尾炎患者进行腹腔镜阑尾切除术。