在内界膜剥除和黄斑裂孔手术中使用自体全血对吲哚菁绿毒性具有保护作用。
Use of autologous whole blood during internal limiting membrane peeling and macular hole surgery is protective for indocyanine green toxicity.
作者信息
Chuang Lan-Hsin, Wang Nan-Kai, Yeung Ling, Chen Yen-Po, Hwang Yih-Shiou, Wu Wei-Chi, Lai Chi-Chun
机构信息
Department of Ophthalmology, Chang-Gung Memorial Hospital, Keelung, Taiwan.
出版信息
Cutan Ocul Toxicol. 2010 Jun;29(2):98-104. doi: 10.3109/15569521003627867.
OBJECTIVE
To compare indocyanine green (ICG)-assisted internal limiting membrane (ILM) peeling with and without autologous whole blood (WB) protection during macular hole repair surgery.
MATERIAL AND METHODS
We retrospectively reviewed 50 eyes with an idiopathic macular hole. Group 1 contained 22 eyes that underwent ILM peeling with WB protection and group 2 contained 28 eyes that underwent ILM peeling without WB. Anatomic and visual results were compared.
RESULTS
After surgery, macular hole closure was achieved in 96% of the group 1 eyes and in 93% of the group 2 eyes. The preoperative mean best-corrected visual acuity (BCVA) was logarithm of the minimum angle of resolution (logMAR) 0.95 in group 1 and logMAR 0.89 in group 2 (p = .544). The postoperative mean BCVA was logMAR 0.57 in group 1 and logMAR 0.92 in group 2 (p = .017).
CONCLUSION
Macular hole surgery protected with WB facilitates improved visual recovery in ICG-assisted ILM peeling.
目的
比较黄斑裂孔修复手术中使用吲哚菁绿（ICG）辅助内界膜（ILM）剥除并采用自体全血（WB）保护与不采用WB保护的效果。
材料与方法
我们回顾性分析了50例特发性黄斑裂孔患者的眼部情况。第1组包含22只接受了采用WB保护的ILM剥除术的眼睛，第2组包含28只接受了未采用WB的ILM剥除术的眼睛。比较两组的解剖学和视觉结果。
结果
术后，第1组96%的眼睛黄斑裂孔闭合，第2组为93%。第1组术前平均最佳矫正视力（BCVA）为最小分辨角对数（logMAR）0.95，第2组为logMAR 0.89（p = 0.544）。第1组术后平均BCVA为logMAR 0.57，第2组为logMAR 0.92（p = 0.017）。
结论
在ICG辅助的ILM剥除术中，采用WB保护的黄斑裂孔手术有助于改善视力恢复。
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