蜘蛛毒液的分子多样性。

Molecular diversity of spider venom.

机构信息

Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia.

出版信息

Biochemistry (Mosc). 2009 Dec;74(13):1505-34. doi: 10.1134/s0006297909130069.

PMID:20210706

Abstract

Spider venom, a factor that has played a decisive role in the evolution of one of the most successful groups of living organisms, is reviewed. Unique molecular diversity of venom components including substances of variable structure (from simple low molecular weight compounds to large multidomain proteins) with different functions is considered. Special attention is given to the structure, properties, and biosynthesis of toxins of polypeptide nature.

摘要

蜘蛛毒液是在进化过程中对最成功的生物群体之一起决定性作用的因素之一，本文对此进行了综述。本文考虑了毒液成分的独特分子多样性，包括具有不同功能的可变结构物质（从简单的低分子量化合物到大型多结构域蛋白质）。特别关注了多肽性质的毒素的结构、性质和生物合成。