Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Am Heart J. 2010 Mar;159(3):421-7. doi: 10.1016/j.ahj.2010.01.004.
Accurate assessment of right atrial pressure (RAP) often requires invasive measurement. With normal RAP, Valsalva increases right internal jugular vein (RIJV) cross sectional area (CSA) 20% to 30%. With high RAP, when venous compliance is low, we hypothesized that the increase in CSA would be blunted and could be detected non-invasively with bedside ultrasound.
RIJV ultrasound images were obtained in 67 patients undergoing right heart catheterization. The median RAP at end-expiration was 7 mm Hg (interquartile range [IQR] 5-9 mm Hg) in patients with normal RAP (n = 47) versus 15 mm Hg (IQR 12-22 mm Hg) in patients with elevated RAP (n = 20). With Valsalva, the median percent change in RIJV CSA was 35% (IQR 19%-79%) versus 5% (IQR 3%-14%) for normal and high RAP, respectively. By receiver operating curve analysis, a <17% increase in RIJV CSA with Valsalva predicted elevated RAP (> or =12 mmHg) with 90% sensitivity, 74% specificity, 94% negative predictive value, and 60% positive predictive value (area under the curve 0.86, P < .001).
An increase in RIJV CSA >17% during Valsalva effectively rules out elevated RAP. This simple bedside technique may be useful to assess central venous pressure and reduce the need for invasive pressure measurement.
准确评估右心房压(RAP)通常需要进行有创测量。在正常 RAP 下,瓦尔萨尔瓦动作使右颈内静脉(RIJV)横截面积(CSA)增加 20%至 30%。在高 RAP 时,当静脉顺应性较低时,我们假设 CSA 的增加会减弱,并且可以通过床边超声无创检测到。
对 67 例行右心导管检查的患者进行 RIJV 超声检查。在正常 RAP 患者(n=47)中,RIJV 在呼气末的中位数 RAP 为 7mmHg(四分位距 [IQR] 5-9mmHg),而在 RAP 升高的患者(n=20)中为 15mmHg(IQR 12-22mmHg)。在瓦尔萨尔瓦动作时,RIJV CSA 的中位数百分比变化分别为 35%(IQR 19%-79%)和 5%(IQR 3%-14%),正常和高 RAP 患者。通过接收者操作曲线分析,RIJV CSA 在瓦尔萨尔瓦动作中增加<17%预测 RAP 升高(>或=12mmHg),其敏感性为 90%,特异性为 74%,阴性预测值为 94%,阳性预测值为 60%(曲线下面积 0.86,P<0.001)。
瓦尔萨尔瓦动作期间 RIJV CSA 的增加>17%有效地排除了 RAP 升高。这种简单的床边技术可能有助于评估中心静脉压并减少有创压力测量的需要。