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Oversulfated chondroitin sulfate is not the sole contaminant in heparin.

作者信息

Pan Jing, Qian Yi, Zhou Xiaodong, Pazandak Andrew, Frazier Sarah B, Weiser Peter, Lu Hong, Zhang Lijuan

出版信息

Nat Biotechnol. 2010 Mar;28(3):203-7; author reply 207-11. doi: 10.1038/nbt0310-203.

DOI:10.1038/nbt0310-203

PMID:20212477

Abstract

摘要

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本文引用的文献

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The Quantification of Glycosaminoglycans: A Comparison of HPLC, Carbazole, and Alcian Blue Methods.

Open Glycosci. 2008 Jan 1;1:31-39. doi: 10.2174/1875398100801010031.

Orthogonal analytical approaches to detect potential contaminants in heparin.

Proc Natl Acad Sci U S A. 2009 Oct 6;106(40):16956-61. doi: 10.1073/pnas.0906861106. Epub 2009 Sep 23.

Analysis of pharmaceutical heparins and potential contaminants using (1)H-NMR and PAGE.

J Pharm Sci. 2009 Nov;98(11):4017-26. doi: 10.1002/jps.21729.

Lessons learned from the contamination of heparin.

Nat Prod Rep. 2009 Mar;26(3):313-21. doi: 10.1039/b819896a. Epub 2009 Jan 19.

Quantitative capillary electrophoresis determination of oversulfated chondroitin sulfate as a contaminant in heparin preparations.

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