Bjornson G L, Scheifele D W, Lajeunesse C, Bell A
Vaccine Evaluation Center, University of British Columbia;
Paediatr Child Health. 1999 Sep;4(6):400-5.
To determine whether reminder notices would improve the timeliness of toddler-age vaccinations.
Prospective, randomized, controlled trial.
Two convenience cohorts of 320 children due to receive either measles-mumps-rubella (MMR) vaccine (at 12 months of age) or diphtheria-pertussis-tetanus (DPT)-inactivated polio (IPV)- Haemophilus influenzae type b (Hib) booster vaccine (at 18 months of age).
Suburban community.
Parents of the identified children were randomly assigned either to a group to receive a reminder notice of pending vaccinations or a control group that did not receive a notice at a ratio of 1:1. Immunization uptake was assessed eights weeks after the initial due date for vaccination.
Information was obtained for 224 children in the MMR group and 227 children in the DPT-IPV-Hib booster group. MMR uptake within eight weeks of the due date was about 90% in both the test and control groups, probably because of publicity surrounding a local college-based measles outbreak. In the DPT-IPV-Hib group, reminder notices had no effect; the uptake rates within eight weeks of the due date were 73.7% to 75.2%. Delays in immunization resulted mostly from parents' scheduling problems and provider-recommended delays. More than half of the parents whose child had delayed immunization did not recall receiving the reminder notice.
Mailed reminders did not increase on-time immunization rates in the second year of a child's life. A telephone call or a more memorable reminder notice may be better suited to catch the attention of parents.
确定提醒通知是否会提高幼儿疫苗接种的及时性。
前瞻性、随机、对照试验。
两个便利队列,共320名儿童,他们将分别接种麻疹-腮腺炎-风疹(MMR)疫苗(12月龄)或白喉-百日咳-破伤风(DPT)-灭活脊髓灰质炎(IPV)-b型流感嗜血杆菌(Hib)加强疫苗(18月龄)。
郊区社区。
将确定儿童的家长按1:1的比例随机分为两组,一组接收即将进行疫苗接种的提醒通知,另一组为未接收通知的对照组。在首次疫苗接种到期日八周后评估免疫接种率。
MMR组224名儿童和DPT-IPV-Hib加强疫苗组227名儿童的信息被获取。在到期日八周内,MMR疫苗的接种率在试验组和对照组中均约为90%,这可能是由于当地一所大学发生麻疹疫情引发的宣传所致。在DPT-IPV-Hib组中,提醒通知没有效果;到期日八周内的接种率为73.7%至75.2%。免疫接种延迟主要是由于家长的日程安排问题和医生建议的延迟。孩子免疫接种延迟的家长中,超过一半不记得收到过提醒通知。
邮寄提醒并没有提高儿童出生后第二年的及时免疫接种率。电话提醒或更能让人记住的提醒通知可能更适合引起家长的注意。