Fodor Eszter, Hagyó Krisztina, Resch Miklós, Somodi Dóra, Németh János
Department of Ophthalmology, Semmelweis University, Budapest, Hungary.
Eur J Ophthalmol. 2010 Sep-Oct;20(5):819-24. doi: 10.1177/112067211002000502.
To measure the lower tear meniscus height (LTMH) with image by Tearscope and using slit-lamp biomicroscopy with or without fluorescein staining.
The lower tear meniscus height was measured in 31 eyes of 31 healthy volunteers (mean age 31.29 years; SD 4.83) with Tearscope and slit lamp with and without fluorescein staining. The mean values of LTMH were measured with different methods and the repeatability of the measurements was statistically analyzed. Measurement of fluorescein tear film break up time (FBUT) and Schirmer test were also performed.
The mean value of LTMH was 0.21 mm (SD 0.07) with Tearscope, 0.20 mm (SD 0.06) with slit lamp without fluorescein staining, and 0.23 mm (SD 0.07) with fluorescein staining. There was no significant difference among the mean values of LTMH with these 3 different measurement methods. Based on the random effect analysis of variance (p=0.05), the measurements were more repeatable with Tearscope-plus than with the other 2 methods. No correlation was found between the LTMH and the results of Schirmer test or FBUT.
The LTMH could be reliably measured with slit-lamp biomicroscopy without staining, but the measurements were more repeatable with Tearscope.
通过泪液镜检查以及使用或不使用荧光素染色的裂隙灯生物显微镜检查，利用图像测量下泪液半月皱襞高度（LTMH）。
对31名健康志愿者（平均年龄31.29岁；标准差4.83）的31只眼睛，使用泪液镜检查以及带或不带荧光素染色的裂隙灯测量下泪液半月皱襞高度。采用不同方法测量LTMH的平均值，并对测量的重复性进行统计学分析。还进行了荧光素泪膜破裂时间（FBUT）测量和泪液分泌试验。
使用泪液镜检查时LTMH的平均值为0.21毫米（标准差0.07），不使用荧光素染色的裂隙灯检查时为0.20毫米（标准差0.06），使用荧光素染色时为0.23毫米（标准差0.07）。这三种不同测量方法的LTMH平均值之间无显著差异。基于方差的随机效应分析（p = 0.05），泪液镜检查法的测量比其他两种方法更具重复性。未发现LTMH与泪液分泌试验结果或FBUT之间存在相关性。
不染色的裂隙灯生物显微镜检查能够可靠地测量LTMH，但泪液镜检查法的测量更具重复性。
