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联合静脉内重组组织型纤溶酶原激活物和血管内治疗伴有串联颅内动脉闭塞的自发性闭塞性颈内动脉夹层。

Combined intravenous recombinant-tissular plasminogen activator and endovascular treatment of spontaneous occlusive internal carotid dissection with tandem intracranial artery occlusion.

机构信息

Hôpital Neurologique et Neurochirurgical P. Wertheimer, Lyon, France.

出版信息

Eur Neurol. 2010;63(4):211-4. doi: 10.1159/000278248. Epub 2010 Mar 9.

DOI:10.1159/000278248
PMID:20215752
Abstract

Internal carotid artery (ICA) dissection with tandem internal carotid and middle cerebral artery occlusion may carry a poor prognosis even if intravenous recombinant-tissular plasminogen activator is administered. A better outcome may be expected with the combination of intravenous thrombolysis and endovascular methods (stenting and thromboaspiration). This procedure was performed in 3 patients who had concurrent ICA dissection and intracerebral occlusion. Endovascular treatment was feasible and safe. All our patients had a good clinical outcome. This potential effective approach may need further validation.

摘要

颈内动脉(ICA)夹层伴串联颈内和大脑中动脉闭塞,即使给予静脉重组组织型纤溶酶原激活剂,预后也可能较差。静脉溶栓联合血管内方法(支架置入和血栓抽吸)可能会有更好的结果。该方法在 3 例同时发生 ICA 夹层和颅内闭塞的患者中进行。血管内治疗是可行和安全的。我们所有的患者都有良好的临床结果。这种潜在的有效方法可能需要进一步验证。

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