Department of Surgical Pathology, Medical, Molecular and Critical Area, Institute of Legal Medicine, University of Pisa, 56126 Pisa (PI), Italy.
IRCSS Neuromed Mediterranean Neurological Institute, Via Atinense 18, 86077 Pozzilli (IS), Italy.
Curr Neuropharmacol. 2022 Aug 3;20(9):1752-1773. doi: 10.2174/1570159X19666210712125929.
Internal carotid artery dissection (ICAD) represents the cause of ictus cerebri in about 20% of all cases of cerebral infarction among the young adult population. ICAD could involve the extracranial and intracranial internal carotid artery (ICA). It could be spontaneous (SICAD) or traumatic (TICAD). It has been estimated that carotid injuries could complicate the 0,32% of cases of general blunt trauma and the percentage seems to be higher in cases of severe multiple traumas. TICAD is diagnosed when neurological symptoms have already occurred, and it could have devastating consequences, from permanent neurological impairment to death. Thus, even if it is a rare condition, a prompt diagnosis is essential. There are no specific guidelines regarding TICAD screening. Nevertheless, TICAD should be taken into consideration when a young adult or middle-aged patient presents after severe blunt trauma. Understanding which kind of traumatic event is most associated with TICAD could help clinicians to direct their diagnostic process. Herein, a review of the literature concerning TICAD has been carried out to highlight its correlation with specific traumatic events. TICAD is mostly correlated to motor vehicle accidents (94/227), specifically to car accidents (39/94), and to direct or indirect head and cervical trauma (76/227). As well, a case report is presented to discuss TICAD forensic implications.
颈内动脉夹层(ICAD)是年轻成人脑梗死的 20%左右的病因。ICAD 可累及颅外和颅内颈内动脉(ICA)。它可能是自发性的(SICAD)或外伤性的(TICAD)。据估计,颈动脉损伤可能会使 0.32%的一般钝性创伤复杂化,而在严重多发伤的情况下,这一比例似乎更高。TICAD 是在出现神经症状时诊断的,它可能会产生毁灭性的后果,从永久性神经损伤到死亡。因此,即使它是一种罕见的疾病,也需要及时诊断。目前还没有关于 TICAD 筛查的具体指南。然而,当年轻成人或中年患者在严重钝性创伤后出现时,应考虑 TICAD。了解哪种创伤性事件与 TICAD 相关性最高,可以帮助临床医生指导他们的诊断过程。在此,对有关 TICAD 的文献进行了回顾,以强调其与特定创伤性事件的相关性。TICAD 主要与机动车事故(94/227)相关,特别是与车祸(39/94)相关,与直接或间接的头部和颈部创伤(76/227)相关。此外,还报告了一个案例讨论 TICAD 的法医学意义。