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丘脑深部脑刺激引起的肌张力障碍性口吃。

Stuttering induced by thalamic deep brain stimulation for dystonia.

机构信息

Neurological Rehabilitation Center Godeshoehe, Waldstrasse 2-10, 53177 Bonn, Germany.

出版信息

J Neural Transm (Vienna). 2010 May;117(5):617-20. doi: 10.1007/s00702-010-0380-0. Epub 2010 Mar 9.

DOI:10.1007/s00702-010-0380-0
PMID:20217438
Abstract

We report a patient in whom deep brain stimulation of the ventral intermediate nucleus of the thalamus (Vim) for treating dystonia reversibly induced stuttering at suboptimal stimulation parameters. Adjustments of stimulation parameters resulted in excellent control of dystonic motor symptoms and complete resolution of speech dysfluency. This is the first report on stuttering as an adverse effect of Vim stimulation which is primarily used to treat tremors of various etiologies.

摘要

我们报告了 1 例深部脑刺激丘脑腹中间核(Vim)治疗肌张力障碍的患者,在亚最佳刺激参数下,该刺激可逆性地引起口吃。调整刺激参数可极好地控制肌张力障碍的运动症状,并完全解决言语不流畅。这是 Vim 刺激引起口吃这一不良反应的首次报道,Vim 刺激主要用于治疗各种病因的震颤。

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Shifted dynamic interactions between subcortical nuclei and inferior frontal gyri during response preparation in persistent developmental stuttering.持续性发展性口吃患者在反应准备过程中皮质下核团和下额前回之间的动态相互作用发生改变。
Brain Struct Funct. 2018 Jan;223(1):165-182. doi: 10.1007/s00429-017-1476-1. Epub 2017 Jul 24.
3
Childhood Neurogenic Stuttering Due to Bilateral Congenital Abnormality in Globus Pallidus: A Case Report and Review of the Literature.

本文引用的文献

1
Stability of symptom control after replacement of impulse generators for deep brain stimulation.深部脑刺激脉冲发生器更换后症状控制的稳定性。
J Neurosurg. 2009 Jun;110(6):1274-7. doi: 10.3171/2009.1.JNS081352.
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Acquired stuttering after pallidal deep brain stimulation for dystonia.
J Neural Transm (Vienna). 2009 Feb;116(2):167-9. doi: 10.1007/s00702-008-0173-x. Epub 2009 Jan 10.
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Deep brain stimulation and tremor.深部脑刺激与震颤
Neurotherapeutics. 2008 Apr;5(2):331-8. doi: 10.1016/j.nurt.2008.01.004.
双侧苍白球先天性异常所致儿童神经性口吃:一例报告并文献复习
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Computational modeling of stuttering caused by impairments in a basal ganglia thalamo-cortical circuit involved in syllable selection and initiation.基于参与音节选择和启动的基底神经节-丘脑-皮质回路损伤的口吃计算建模。
Brain Lang. 2013 Sep;126(3):263-78. doi: 10.1016/j.bandl.2013.05.016. Epub 2013 Jul 19.
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Current and future medical treatment in primary dystonia.原发性肌张力障碍的当前和未来的治疗方法。
Ther Adv Neurol Disord. 2012 Jul;5(4):221-40. doi: 10.1177/1756285612447261.
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Bilateral, pallidal, deep-brain stimulation in primary generalised dystonia: a prospective 3 year follow-up study.原发性全身性肌张力障碍的双侧苍白球深部脑刺激:一项前瞻性3年随访研究。
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N Engl J Med. 2006 Nov 9;355(19):1978-90. doi: 10.1056/NEJMoa063618.
6
Sources and effects of electrode impedance during deep brain stimulation.脑深部电刺激期间电极阻抗的来源及影响
Clin Neurophysiol. 2006 Feb;117(2):447-54. doi: 10.1016/j.clinph.2005.10.007. Epub 2005 Dec 22.
7
Tissue and electrode capacitance reduce neural activation volumes during deep brain stimulation.在深部脑刺激过程中,组织和电极电容会减小神经激活体积。
Clin Neurophysiol. 2005 Oct;116(10):2490-500. doi: 10.1016/j.clinph.2005.06.023.
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Bilateral deep-brain stimulation of the globus pallidus in primary generalized dystonia.原发性全身性肌张力障碍中双侧苍白球深部脑刺激术
N Engl J Med. 2005 Feb 3;352(5):459-67. doi: 10.1056/NEJMoa042187.
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Stuttering and the basal ganglia circuits: a critical review of possible relations.口吃与基底神经节回路:对可能关系的批判性综述
J Commun Disord. 2004 Jul-Aug;37(4):325-69. doi: 10.1016/j.jcomdis.2004.03.001.
10
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