Seidensticker F, Schaumberger M, Ulbig M, Ludwig K, Kampik A, Lackerbauer C-A
Universitätsaugenklinik München, Centrum für refraktive Therapie, München.
Klin Monbl Augenheilkd. 2010 Jun;227(6):483-8. doi: 10.1055/s-0028-1109956. Epub 2010 Mar 9.
The aim of this study was to investigate the clinical long-term outcome of the 1CU posterior chamber IOL. Objective accommodative dynamics as well as measured data were assessed subjectively three months and 72 months after implantation.
Retrospectively, 26 eyes after uneventful cataract surgery with 1CU IOL implantation were included. In 26 eyes (group I), the change of the anterior IOL reflex without and under stimulation with pilocarpine 1 %, and cyclopentolate (pseudophakic-accommodation), and maximum obfuscation under best corrected visual acuity (BCVA) settings (pseudo-accommodation) were examined. In 20 eyes (group II) the influence of the laser capsulotomy on the pseudophakic-accommodation was evaluated.
Eyes, stimulated by pilocarpine 1 %, have an anterior (-) shift of the IOL reflex of -0.59 +/- 0.28 mm (pseudophakic-accommodation) after 3 months and -0.49 +/- 0.27 mm after 50.8 months (p < 0.001). The mean obfuscation under BCVA level (pseudo-accommodation) was 1.5 diopters (D). Laser capsulotomy was performed after 21 +/- 15 months in the mean. A change of the anterior reflex of the IOL of -0.5 +/- 0.3 mm before and after Nd:YAG laser treatment did not show any statistical significance.
Under application of pilocarpine 1 % and cyclopentolate a small movement of the 1CU-IOL was examined. The amount of the anterior/posterior shift of the IOL reflex was stable over the follow-up period but is not sufficient to provide full presbyopic correction.
本研究旨在调查1CU后房型人工晶状体的临床长期效果。在植入后三个月和72个月时,对主观目标调节动力学以及测量数据进行评估。
回顾性纳入26例白内障手术顺利并植入1CU人工晶状体的眼。在26只眼中(第一组),检查了在无1%毛果芸香碱和有1%毛果芸香碱刺激以及环喷托酯(假晶状体调节)情况下前房人工晶状体反射的变化,以及在最佳矫正视力(BCVA)设置下的最大模糊度(假调节)。在20只眼中(第二组),评估了激光囊切开术对假晶状体调节的影响。
1%毛果芸香碱刺激的眼,人工晶状体反射在前房的移位在植入后3个月时为-0.59±0.28mm(假晶状体调节),在50.8个月时为-0.49±0.27mm(p<0.001)。BCVA水平下的平均模糊度(假调节)为1.5屈光度(D)。平均在21±15个月后进行了激光囊切开术。钕:钇铝石榴石激光治疗前后人工晶状体前反射的变化为-0.5±0.3mm,无统计学意义。
在应用1%毛果芸香碱和环喷托酯的情况下,观察到1CU人工晶状体有小幅度移动。在随访期间,人工晶状体反射的前后移位量是稳定的,但不足以提供完全的老视矫正。