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植入可调节后房型人工晶状体1CU的患者在钕:钇铝石榴石晶状体囊切开术后的调节功能

Accommodation after Nd: YAG capsulotomy in patients with accommodative posterior chamber lens 1CU.

作者信息

Nguyen Nhung X, Seitz B, Reese S, Langenbucher A, Küchle M

机构信息

Department of Ophthalmology, University Erlangen-Nürnberg, Erlangen, Germany.

出版信息

Graefes Arch Clin Exp Ophthalmol. 2005 Feb;243(2):120-6. doi: 10.1007/s00417-004-1041-5. Epub 2004 Dec 14.

Abstract

PURPOSE

After initial encouraging results with the accommodative 1CU posterior chamber lens (PCIOL), we investigated the rate, the postoperative time point of posterior capsular opacification (PCO) necessitating YAG capsulotomy and the accommodative range after Nd: YAG capsulotomy in patients with 1CU-PCIOL.

PATIENTS AND METHODS

This prospective clinical study included 65 patients who underwent phacoemulsification and implantation of the accommodative 1CU-PCIOL with postoperative follow-up from 3 to 24 months. Postoperative examination was performed 3, 6 and 12 months after surgery, then before and 6 weeks after Nd: YAG capsulotomy. Measurements included: the best corrected distance visual acuity, distance refraction, near visual acuity (Birkhauser charts in 35 cm) obtained with best distance correction, accommodative range measured by subjective near point with an accodommometer and defocusing with a visual acuity fall to 0.4.

RESULTS

Both best corrected distance visual acuity (1.1+/-0.1) and near visual acuity with best distance correction (0.4+/-0.1) remained stable over the follow-up period until 12 months postoperatively. The accommodative range determined by near point was stable (mean 2.0+/-0.5 D). Also, the defocusing range remained stable over 12 months (1.8+/-0.4 D). A clinically relevant posterior capsule opacification with a significant decrease of visual acuity (0.4+/-0.2) and a need for Nd: YAG capsulotomy was diagnosed in 12 patients between 15 and 22 (mean 20+/-4, median 20) months postoperatively. All capsulotomies were performed without complication. Six weeks after capsulotomy, best corrected distance visual acuity was improved (1.1+/-0.1), near visual acuity with best distance correction was 0.4+/-0.1 and the accommodative range determined by near point was 1.95+/-0.6 D and by defocusing was 1.88+/-0.47 D. Six weeks after capsulotomy, measurements of the accommodative range did not show any statistical difference to the 12-month results before the occurrence of PCO (P>0.5).

CONCLUSIONS

A clinically relevant PCO with a significant decrease of visual acuity necessitating Nd: YAG capsulotomy occurred mainly after 15 postoperative months in patients with 1CU. Our results indicate that Nd: YAG capsulotomy may not affect the accommodation ability of the 1CU. Nevertheless, long-term studies are needed to further analyze the accommodative properties.

摘要

目的

在可调节的1CU后房型人工晶状体(PCIOL)取得初步令人鼓舞的结果后,我们调查了植入1CU-PCIOL的患者后囊膜混浊(PCO)需要进行YAG激光后囊切开术的发生率、术后时间点以及Nd:YAG激光后囊切开术后的调节范围。

患者与方法

这项前瞻性临床研究纳入了65例行超声乳化白内障吸除术并植入可调节1CU-PCIOL的患者,术后随访3至24个月。术后分别在术后3、6和12个月进行检查,然后在Nd:YAG激光后囊切开术前及术后6周进行检查。测量指标包括:最佳矫正远视力、远屈光不正、在最佳远矫正状态下测得的近视力(使用35cm的Birkhauser视力表)、使用调节计通过主观近点测量的调节范围以及视力下降至0.4时的散焦情况。

结果

在随访期直至术后12个月,最佳矫正远视力(1.1±0.1)和在最佳远矫正状态下的近视力(0.4±0.1)均保持稳定。通过近点确定 的调节范围稳定(平均2.0±0.5D)。此外,散焦范围在12个月内也保持稳定(1.8±0.4D)。12例患者在术后15至22个月(平均20±4个月,中位数20个月)被诊断为具有临床相关性的后囊膜混浊,视力显著下降(0.4±0.2),需要进行Nd:YAG激光后囊切开术。所有后囊切开术均无并发症发生。后囊切开术后6周,最佳矫正远视力得到改善(1.1±0.1),在最佳远矫正状态下的近视力为0.4±0.1,通过近点确定的调节范围为1.95±0.6D,通过散焦确定的调节范围为1.88±0.47D。后囊切开术后6周,调节范围的测量结果与PCO发生前12个月的结果相比,未显示出任何统计学差异(P>0.5)。

结论

在植入1CU的患者中,具有临床相关性且导致视力显著下降需要进行Nd:YAG激光后囊切开术的PCO主要发生在术后15个月之后。我们的结果表明,Nd:YAG激光后囊切开术可能不会影响1CU的调节能力。然而,需要进行长期研究以进一步分析其调节特性。

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