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猫的胰岛素抵抗

Insulin resistance in cats.

作者信息

Scott-Moncrieff J Catharine

机构信息

Department of Veterinary Clinical Sciences, Purdue University, VCS/LYNN, 625 Harrison Street, West Lafayette, IN 47907, USA.

出版信息

Vet Clin North Am Small Anim Pract. 2010 Mar;40(2):241-57. doi: 10.1016/j.cvsm.2009.10.007.

DOI:10.1016/j.cvsm.2009.10.007
PMID:20219486
Abstract

Insulin resistance is defined as decreased sensitivity to insulin. Insulin resistance is an important component of the pathogenesis of type 2 diabetes mellitus (DM), and resolution of peripheral insulin resistance in cats with type 2 DM together with good glycemic control may result in diabetic remission. In insulin-dependent diabetic cats, insulin resistance is manifested clinically as an inadequate response to an appropriate pharmacologic dose of insulin. This article focuses on the clinical problem of insulin resistance in insulin-dependent diabetic cats.

摘要

胰岛素抵抗被定义为对胰岛素的敏感性降低。胰岛素抵抗是2型糖尿病(DM)发病机制的一个重要组成部分,2型糖尿病猫外周胰岛素抵抗的缓解以及良好的血糖控制可能会导致糖尿病缓解。在胰岛素依赖型糖尿病猫中,胰岛素抵抗在临床上表现为对适当药理剂量的胰岛素反应不足。本文重点关注胰岛素依赖型糖尿病猫胰岛素抵抗的临床问题。

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