Ngeow Wei Cheong
Department of Oral & Maxillofacial Medicine and Surgery, School of Clinical Dentistry, University of Sheffield, Sheffield, England.
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2010 Mar;109(3):357-66. doi: 10.1016/j.tripleo.2009.06.030.
Scar formation is important for normal wound healing but proliferation of scar tissue from the epineurium in response to a nerve injury will result in impediment to the regenerating axons that need to traverse the repaired site. This article reviews the events that occur after peripheral nerve transection and the challenges that need to be addressed to reduce scarring in order to improve nerve regeneration.
瘢痕形成对正常伤口愈合很重要，但神经损伤后神经外膜瘢痕组织的增殖会阻碍需要穿过修复部位的再生轴突。本文综述了周围神经横断后发生的事件以及为减少瘢痕形成以改善神经再生而需要应对的挑战。
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