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肺移植术后播散性中枢神经系统感染:一例成功康复的病例报告

Disseminated central nervous system infection after lung transplantation: A case report with successful recovery.

作者信息

Paajanen Juuso, Halme Maija, Palomäki Maarit, Anttila Veli-Jukka

机构信息

Department of Pulmonary Medicine, Heart and Lung Center, University of Helsinki and Helsinki University Hospital, Finland.

Department of Radiology, University of Helsinki and Helsinki University Hospital, Finland.

出版信息

Med Mycol Case Rep. 2019 Mar 16;24:37-40. doi: 10.1016/j.mmcr.2019.03.003. eCollection 2019 Jun.

DOI:10.1016/j.mmcr.2019.03.003
PMID:30956943
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6431731/
Abstract

species are fungal opportunistic pathogens frequently seen in chronic lung diseases such as in cystic fibrosis (CF). They can cause a wide spectrum of diseases mainly in immunodeficient patients. Invasive, disseminated infections with poor prognosis have been described after lung transplantation. We present a CF-patient with disseminated infection after lung transplantation. The patient had skin, surgical wound, spinal cord, and brain involvements. She recovered fully after prolonged course of voriconazole treatment.

摘要

该物种是真菌性机会致病菌,常见于慢性肺部疾病,如囊性纤维化(CF)。它们主要可在免疫功能低下的患者中引发多种疾病。肺移植后曾有侵袭性、播散性感染且预后不良的报道。我们报告一例肺移植后发生播散性感染的CF患者。该患者皮肤、手术伤口、脊髓和脑部均受累。在接受长时间伏立康唑治疗后她完全康复。

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Transpl Infect Dis. 2018 Feb;20(1). doi: 10.1111/tid.12792. Epub 2017 Nov 27.
2
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Clin Chest Med. 2017 Sep;38(3):511-520. doi: 10.1016/j.ccm.2017.04.011. Epub 2017 May 20.
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Clinical outcome of cystic fibrosis patients colonized by Scedosporium species following lung transplantation: A single-center 15-year experience.
Pharmaceutics. 2023 Dec 26;16(1):34. doi: 10.3390/pharmaceutics16010034.
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Update on therapeutic approaches for invasive fungal infections in adults.成人侵袭性真菌感染治疗方法的最新进展。
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