Al-Bayyari Nahla Subhi, Abu-Heija Adel Taha
Department of Applied Sciences, Al-Huson University College, Al-Balqa Applied University, Irbid, Jordan.
Ann Saudi Med. 2010 Mar-Apr;30(2):134-40. doi: 10.4103/0256-4947.60519.
Estimated intrauterine fetal weight (EIUFW) is important for reducing prenatal mortality and morbidity through early detection of faltering growth. Our objectives were to develop patterns of ultrasonically determined EIUFW by gestational age, for normal singleton pregnancies, and to assess the effect of a number of variables on EIUFW.
Ultrasonically, EIUFW was obtained from 600 pregnant women who were at 20 to 42 weeks of gestation (WG). EIUFW was categorized into low weight and normal weight using the tenth and twentieth percentile as the cut-off points. Logistic regression was used to calculate the odds ratio and their 95% confidence limits for a number of risk factors hypothesized to be associated with low fetal weight. EIUFW percentiles (twenty-fifth, fiftieth, and seventy-fifth), by gestational age and sex, were calculated for singleton pregnancies.
Up to 32 WG there was no statistically significant difference between male and female fetuses in EIUFW. Between 32 and 39 WG males had significantly (P< .05) higher fetal weight than females. Charts of ultrasonically determined EIUFW by gestational age and sex for singleton pregnancies were created. A number of variables were significantly associated with EIUFW, such as pregnancy weight gain, maternal hemoglobin level, frequency of antenatal visits, smoking status, and fetal sex.
Weight gain during pregnancy should be encouraged for pregnant mothers who gain less than one kilogram per month in the second and third trimester. A prospective study on a national representative sample in Jordan is needed to generate our own standards for fetal growth.
估计胎儿宫内体重(EIUFW)对于通过早期发现生长迟缓来降低产前死亡率和发病率至关重要。我们的目标是为正常单胎妊娠制定按孕周通过超声测定的EIUFW模式,并评估多个变量对EIUFW的影响。
通过超声从600名妊娠20至42周(WG)的孕妇获取EIUFW。以第十和第二十百分位数作为分界点,将EIUFW分为低体重和正常体重。使用逻辑回归计算一些假设与低胎儿体重相关的危险因素的比值比及其95%置信区间。计算单胎妊娠按孕周和性别的EIUFW百分位数(第二十五、第五十和第七十五百分位数)。
在32周WG之前,男、女胎儿的EIUFW无统计学显著差异。在32至39周WG之间,男性胎儿体重显著高于女性(P<0.05)。创建了单胎妊娠按孕周和性别的超声测定EIUFW图表。一些变量与EIUFW显著相关,如孕期体重增加、孕妇血红蛋白水平、产前检查频率、吸烟状况和胎儿性别。
对于在孕中期和孕晚期每月体重增加不足1千克的孕妇,应鼓励其增加孕期体重。需要在约旦进行一项具有全国代表性样本的前瞻性研究,以制定我们自己的胎儿生长标准。