Glanz S, Maceyko R F, Camisa C, Tomecki K J
Department of Dermatology, Cleveland Clinic Foundation, Ohio 44195-5032.
Cutis. 1991 Mar;47(3):167-72.
Crohn's disease is an idiopathic inflammatory process that predominantly affects the gastrointestinal tract. Numerous extraintestinal manifestations of Crohn's disease involving the skin and mucous membranes have been reported in patients with documented intestinal disease. We report here on two patients who presented with multiple manifestations of Crohn's disease before intestinal disease was diagnosed. We review the mucocutaneous manifestations of Crohn's disease with an emphasis on presentations that precede gastrointestinal involvement.
克罗恩病是一种主要累及胃肠道的特发性炎症性疾病。在有肠道疾病记录的患者中,已报告了许多克罗恩病累及皮肤和黏膜的肠外表现。我们在此报告两名患者,他们在肠道疾病被诊断之前就出现了克罗恩病的多种表现。我们回顾了克罗恩病的皮肤黏膜表现,重点关注胃肠道受累之前的表现。