Wong C-H, Tan S-H, Kurup A, Tan A B-H
Department of Hand Surgery, Singapore General Hospital, Singapore.
Eur J Clin Microbiol Infect Dis. 2004 Dec;23(12):909-11. doi: 10.1007/s10096-004-1237-y. Epub 2004 Nov 13.
Reported here is a rare case of recurrent necrotizing fasciitis due to methicillin-resistant Staphylococcus aureus (MRSA). A 46-year-old female with poorly controlled diabetes and chronic ingestion of steroid-containing medications was admitted for treatment of necrotizing fasciitis of the right thigh. Three months following hospital discharge she was readmitted with necrotizing fasciitis of the left hand. On both occasions, MRSA was isolated from tissue cultures obtained during surgical debridement. Patients who develop necrotizing fasciitis are predisposed to severe soft tissue infections due to associated comorbid conditions such as diabetes mellitus. Recurrent soft tissue infection in a patient with previous MRSA-related necrotizing fasciitis should therefore be treated with a high index of suspicion.
本文报告了一例罕见的由耐甲氧西林金黄色葡萄球菌（MRSA）引起的复发性坏死性筋膜炎病例。一名46岁女性，糖尿病控制不佳且长期服用含类固醇药物，因右大腿坏死性筋膜炎入院治疗。出院三个月后，她因左手坏死性筋膜炎再次入院。两次发病时，手术清创获取的组织培养物中均分离出MRSA。患有坏死性筋膜炎的患者由于合并症（如糖尿病）易发生严重的软组织感染。因此，对于既往有MRSA相关坏死性筋膜炎的患者，若出现复发性软组织感染，应高度怀疑并进行治疗。
