Ozeç Ilker, Taşdemir Ufuk, Gümüş Cesur, Solak Orhan
Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Cumhuriyet University, Sivas, Turkey.
J Oral Maxillofac Surg. 2010 May;68(5):1032-7. doi: 10.1016/j.joms.2009.12.023. Epub 2010 Mar 12.
The aim of this study was to evaluate the presence of probable diffused local anesthetic solution at and anesthesia of palatal tissues after buccal injection of 4% articaine hydrochloride (HCl) with 1:100,000 epinephrine or 1:200,000 epinephrine at the premolar and molar region.
Thirty volunteers received maxillary buccal injections of 4% articaine HCl with 1:100,000 epinephrine or 1:200,000 epinephrine bilaterally to the first premolar or first molar. Magnetic resonance images were obtained before and 5 minutes after local anesthetic injections, and a visual evaluation was done to determine the presence of local anesthetic solution at palatal tissues. Anesthesia of palatal tissues after buccal injection was assessed by needle-prick stimulation pain with a visual analog scale (VAS). The Kruskal-Wallis test was used for comparison of the VAS values.
The visual evaluation of the magnetic resonance images did not show any signal change as an indicator of the presence of local anesthetic solution at the palatal region. Most of the volunteers described moderate or severe pain with needle-prick stimulation. The mean VAS score for needle-prick stimulation was 86.33 +/- 39.45 mm (1:100,000 epinephrine) and 87.0 +/- 36.28 mm (1:200,000 epinephrine) in the first premolar region and 57.20 +/- 46.69 mm (1:100,000 epinephrine) and 75.53 +/- 49.78 mm (1:200,000 epinephrine) in the molar region (P > .05).
We could not establish the presence of anesthesia or 4% articaine HCl at the palatal tissues after buccal injection. Maxillary tooth removal without palatal injection requires further objective investigations.
本研究旨在评估在双尖牙和磨牙区域颊侧注射含1:100,000肾上腺素或1:200,000肾上腺素的4%盐酸阿替卡因后,腭部组织处可能存在的弥散性局部麻醉溶液情况以及腭部组织的麻醉效果。
30名志愿者双侧上颌颊侧分别注射含1:100,000肾上腺素或1:200,000肾上腺素的4%盐酸阿替卡因至第一双尖牙或第一磨牙处。在局部麻醉剂注射前及注射后5分钟获取磁共振图像,并通过视觉评估来确定腭部组织处局部麻醉溶液的存在情况。颊侧注射后腭部组织的麻醉效果通过视觉模拟评分法(VAS)进行针刺刺激疼痛评估。采用Kruskal-Wallis检验比较VAS值。
磁共振图像的视觉评估未显示腭部区域存在局部麻醉溶液的任何信号变化迹象。大多数志愿者描述针刺刺激时有中度或重度疼痛。在第一双尖牙区域,针刺刺激的平均VAS评分为86.33±39.45毫米(1:100,000肾上腺素组)和87.0±36.28毫米(1:200,000肾上腺素组);在磨牙区域,平均VAS评分为57.20±46.69毫米(1:100,000肾上腺素组)和75.53±49.78毫米(1:200,000肾上腺素组)(P>.05)。
我们无法证实颊侧注射后腭部组织存在麻醉或4%盐酸阿替卡因。不进行腭部注射的上颌牙拔除术需要进一步的客观研究。