Center for Bioelectronics and Biosensors, Biodesign Institute, Arizona State University, Tempe, AZ 85287, USA.
Science. 2010 Mar 12;327(5971):1363-6. doi: 10.1126/science.1186476.
We demonstrated an electrochemical microscopy technique based on the detection of variations in local electrochemical current from optical signals arising from surface plasmon resonance. It enables local electrochemical measurements (such as voltammetry and amperometry) with high spatial resolution and sensitivity, because the signal varies with current density rather than current. The imaging technique is noninvasive, scanning-free, and fast, and it constitutes a powerful tool for studying heterogeneous surface reactions and for analyzing trace chemicals.
我们展示了一种基于表面等离子体共振产生的光学信号检测局部电化学电流变化的电化学显微镜技术。它能够实现具有高空间分辨率和灵敏度的局部电化学测量（如伏安法和安培法），因为信号随电流密度而变化，而不是电流。该成像技术是非侵入式、无扫描且快速的，它构成了研究异质表面反应和分析痕量化学物质的有力工具。
