Department of Radiation Oncology, University of California San Diego, 3855 Health Sciences Dr, La Jolla, CA 92037-0843, USA.
Phys Med Biol. 2010 Apr 7;55(7):1863-73. doi: 10.1088/0031-9155/55/7/005. Epub 2010 Mar 12.
Currently, high-precision delivery in stereotactic radiosurgery (SRS) is achieved via high-precision target localization and rigid patient immobilization. Rigid patient immobilization can result in, however, patient discomfort, which is exacerbated by the long duration of SRS treatments and may induce patient movement. To address this issue, we developed a new SRS technique that is aimed to minimize patient discomfort while maintaining high-precision treatment, based on a less-rigid patient immobilization combined with continuous patient motion monitoring. In this paper, we examine the feasibility of this new technique. An anthropomorphic head phantom is used to check the accuracy of a 3D surface imaging system that provides the monitoring. Volunteers are used to study patient motion inside a new type of head mold that is used for minimal immobilization. Results show that for different couch angles, the difference between the phantom positions recorded by the surface imaging system and by an infrared optical tracking system was within 1 mm in displacements and 1 degrees in rotation. The motion detected by both systems during couch shifts is within 1 mm agreement. The average maximum volunteer head motion in the head mold during the 20 min interval in any direction was 0.7 mm (range: 0.4-1.1 mm). Patient motion due to couch motion was always less than 0.2 mm. We conclude that motion inside the minimally immobilizing head mold is small and can be accurately detected by real-time surface imaging.
目前,立体定向放射外科(SRS)中的高精度投递是通过高精度的目标定位和刚性的患者固定来实现的。然而,刚性患者固定会导致患者不适,而 SRS 治疗的持续时间长,可能会加剧患者的运动。为了解决这个问题,我们开发了一种新的 SRS 技术,该技术旨在在保持高精度治疗的同时最小化患者不适,其基础是一种不太刚性的患者固定和连续的患者运动监测。本文研究了这种新技术的可行性。使用人体头部模拟体来检查提供监测的 3D 表面成像系统的准确性。志愿者被用于研究在新型头部模具中最小化固定时患者的运动。结果表明,对于不同的治疗床角度,表面成像系统和红外光学跟踪系统记录的模拟体位置之间的差异在位移上小于 1 毫米,在旋转上小于 1 度。在治疗床移动过程中,两个系统检测到的运动在 1 毫米以内一致。在任何方向上,志愿者在头部模具中 20 分钟间隔内的平均最大头部运动幅度为 0.7 毫米(范围:0.4-1.1 毫米)。由于治疗床运动导致的患者运动始终小于 0.2 毫米。我们得出结论,最小化固定的头部模具内的运动幅度较小,并且可以通过实时表面成像准确检测到。