General Practice and Primary Care Research Unit, Department of Public Health & Primary Care, Institute of Public Health, University of Cambridge, and Addenbrooke's Hospital, Cambridge University Hospitals' NHS Foundation Trust, Robinson Way, Cambridge, CB2 0SR, UK.
Qual Life Res. 2010 Jun;19(5):619-29. doi: 10.1007/s11136-010-9631-7. Epub 2010 Mar 12.
To report the experience of using the SEIQoL-DW for the measurement of quality of life with patients with advanced COPD and consider its feasibility, acceptability and appropriateness for a Phase III randomised controlled trial (RCT).
The SEIQoL-DW was administered according to its instructions within a Phase II RCT 3-5 times per patient, across 13 patients and the process audio-recorded. Quantitative and qualitative criteria were used to assess feasibility, acceptability and appropriateness. Qualitative analysis of the transcripts and fieldwork notes was conducted using Framework Analysis.
The SEIQoL-DW steps (of identifying five quality of life cues, rating their functioning and importance) were completed at 48/51 interviews. However, some respondents were overwhelmed by the scripted introduction, experienced difficulty with cue identification, and focused only on certain types of cues (Step 1); some had difficulty interpreting and rating the concept of Step 2; and some had difficulty interpreting 'importance' and manipulating the SEIQoL-DW disc (Step 3).
Patients with advanced COPD were able to complete the SEIQoL-DW but analysis of its administration identified practical and conceptual concerns which question the validity of the results obtained. Suggestions for the development of the SEIQoL-DW and future feasibility studies are given.
报告使用 SEIQoL-DW 测量晚期 COPD 患者生活质量的经验，并考虑其在 III 期随机对照试验（RCT）中的可行性、可接受性和适宜性。
根据 SEIQoL-DW 的说明，对 13 名患者进行了 3-5 次测量，并对过程进行了录音。使用定量和定性标准评估可行性、可接受性和适宜性。对转录本和实地工作记录进行了框架分析的定性分析。
在 48/51 次访谈中完成了 SEIQoL-DW 的步骤（识别五个生活质量线索，对其功能和重要性进行评分）。然而，一些受访者对脚本介绍感到不知所措，在识别线索方面遇到困难，并且只关注某些类型的线索（步骤 1）；一些人难以理解和评分步骤 2 的概念；一些人难以理解“重要性”并操纵 SEIQoL-DW 磁盘（步骤 3）。
晚期 COPD 患者能够完成 SEIQoL-DW，但对其管理的分析提出了实际和概念上的问题，这些问题对所获得结果的有效性提出了质疑。为 SEIQoL-DW 的发展和未来可行性研究提出了建议。
