Department of Dermatology, Center for Dermatology Research, Wake Forest University School of Medicine, Winston-Salem, North Carolina 27157-1071, USA.
J Am Acad Dermatol. 2010 Apr;62(4):646-54. doi: 10.1016/j.jaad.2009.05.030.
Pyoderma gangrenosum is a rare and often painful skin disease that can be unpredictable in its response to treatment. There is currently no gold standard of treatment or published algorithm for choice of therapy. The majority of data comes from case studies that lack a standard protocol not only for treatment administration but also for the objective assessment of lesion response to a specific therapy. This review provides an update to the treatment of pyoderma gangrenosum with a particular focus on new systemic therapies.
坏疽性脓皮病是一种罕见且常伴有疼痛的皮肤疾病，其对治疗的反应难以预测。目前，尚无治疗的金标准或可供选择的治疗方案的既定算法。大多数数据来自病例研究，这些研究不仅缺乏治疗管理的标准方案，而且缺乏对特定治疗方法对病变反应的客观评估。本文综述了坏疽性脓皮病的治疗方法，特别关注新的系统治疗方法。
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