Department of General Surgery, Sinai Hospital of Baltimore, Baltimore, MD 21215, USA.
J Wound Ostomy Continence Nurs. 2010 Mar-Apr;37(2):209-13. doi: 10.1097/WON.0b013e3181d0feea.
Descending necrotizing mediastinitis is a rare but serious infection of the interpleural spaces and mediastinal connective tissue from the cervical region to the diaphragm that spreads rapidly along fascial planes.
This report describes an unusual presentation of descending necrotizing mediastinitis in an otherwise healthy 25-year-old woman infected with methicillin-resistant Staphylococcus aureus, whose management required open sternotomy with frequent debridement.
The mainstays of descending necrotizing mediastinitis management are early diagnosis, aggressive surgical debridement and drainage, and appropriate antibiotic therapy.
下行性坏死性纵隔炎是一种罕见但严重的感染，感染部位位于颈部分隔至膈肌的胸膜间隙和纵隔结缔组织，其沿着筋膜平面迅速扩散。
本报告描述了一例不典型的耐甲氧西林金黄色葡萄球菌感染的 25 岁健康女性下行性坏死性纵隔炎，该患者需要行胸骨正中切开术并频繁清创，治疗方法较为特殊。
下行性坏死性纵隔炎的主要治疗方法是早期诊断、积极的手术清创和引流以及适当的抗生素治疗。
