CSPP@Alliant International University, 10455 Pomerado Rd, San Diego, CA 92131, USA.
Appl Psychophysiol Biofeedback. 2010 Sep;35(3):199-206. doi: 10.1007/s10484-010-9128-8.
Functional abdominal pain (FAP) causes disruption of daily activities/missed school days, over utilization of healthcare, unnecessary surgeries, and anxiety in 10-15% of children. Its etiology is not clearly understood, however the success of several clinical protocols suggests that autonomic dysregulation is a factor. In this study autonomic activity, including heart rate variability (HRV), was compared between children with FAP and a comparison group. Twenty children with FAP and 10 children without FAP between the ages of 5 and 17 years old were compared on autonomic regulation using an ambulatory system at baseline and 8 weeks later. Children with FAP participated in 6 sessions of HRV biofeedback aimed at normalizing autonomic balance. At baseline, children with FAP appear to have more autonomic dysregulation than children without FAP. After completing HRV biofeedback, the FAP group was able to significantly reduce their symptoms in relation to significantly increasing their autonomic balance. In a sample of children with FAP, it appears that HRV biofeedback treatment improved their symptoms and that a change in vagal tone was a potential mediator for this improvement. The present study appears to point to excessive vagal withdrawal as an underlying mechanism of FAP.
功能性腹痛（FAP）导致 10-15%的儿童日常活动中断/缺课、过度利用医疗保健、不必要的手术和焦虑。其病因尚不清楚，但多项临床方案的成功表明自主神经调节异常是一个因素。在这项研究中，我们比较了 FAP 儿童和对照组之间的自主活动，包括心率变异性（HRV）。使用动态系统，我们在基线和 8 周后比较了 20 名 FAP 儿童和 10 名无 FAP 儿童的自主调节情况。FAP 儿童参加了 6 次 HRV 生物反馈课程，旨在使自主平衡正常化。在基线时，FAP 儿童似乎比无 FAP 儿童的自主神经调节更紊乱。完成 HRV 生物反馈后，FAP 组能够显著减轻症状，同时显著增加自主平衡。在 FAP 儿童的样本中，HRV 生物反馈治疗似乎改善了他们的症状，迷走神经张力的变化可能是这种改善的潜在介导因素。本研究似乎表明，过度的迷走神经撤退是 FAP 的潜在机制。
