Jegede A S
Department of Sociology, Faculty of the Social Sciences, University of Ibadan, Ibadan, Nigeria.
Afr J Med Med Sci. 2009 Jun;38 Suppl 2:31-40.
Unlike biomedical research, social and behavioural research has not been thought to require rigorous or mandatory ethical review on the assumption that it can do no harm. As a result, little or no attention is paid to its involvement in health researches. This paper discusses the ethical challenges of social and behavioural research in cancer to identify potential areas for research. Inferences were made from documentary analysis of characteristics of cancer patients. A total of 76 papers were reviewed covering the period from1960 to 2007. The data shows that conducting social and behavioural research on cancer patients in Africa is associated with ethical challenges. These include; respect for person and autonomy, risk minimization, exploitation, inducement and compensation, benefit sharing, gaining access to participant, third party issue, informed consent, coercion, discrimination, conflict of interest and scientific misconduct. The paper concludes that cultural challenges of cancer research, management and administration of informed consent, access to research participant, compensation of research participant and benefit sharing are major potential areas of research.
与生物医学研究不同,社会和行为研究一直被认为无需进行严格或强制性的伦理审查,因为人们假定它不会造成伤害。因此,很少或根本没有关注其在健康研究中的参与情况。本文讨论了癌症领域社会和行为研究的伦理挑战,以确定潜在的研究领域。通过对癌症患者特征的文献分析得出推论。共审查了1960年至2007年期间的76篇论文。数据表明,在非洲对癌症患者进行社会和行为研究存在伦理挑战。这些挑战包括:尊重个人和自主性、将风险降至最低、剥削、诱导和补偿、利益分享、接触参与者、第三方问题、知情同意、 coercion(此处英文原文有误,推测可能是“coercion”,意为“强迫”)、歧视、利益冲突和科研不当行为。本文得出结论,癌症研究的文化挑战、知情同意的管理、接触研究参与者、研究参与者的补偿和利益分享是主要的潜在研究领域。