The MOE Key Laboratory for Standardization of Chinese Medicines, Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, Shanghai 201210, PR China.
Fitoterapia. 2010 Sep;81(6):610-3. doi: 10.1016/j.fitote.2010.03.003. Epub 2010 Mar 15.
Phytochemical investigation of the ethanol extract of the leaves of Andrographis paniculata yielded one novel diterpene (13R, 14R) 3, 13, 14, 19-tetrahydroxy-ent-labda-8 (17), 11-dien-16, 15-olide 1 which has an uncommon cis-diol groups in the lactone moiety, and 3, 19-isopropylidene-14-deoxy-ent-labda-8 (17), 13-dien-16, 15-olide 2, probably an artifact diterpene, together with eight known diterpenoids 3-10. The structures of these compounds were determined on the basis of spectral methods. The structure and stereochemistry of 1 was confirmed by X-ray crystallographic analyses.
对穿心莲叶的乙醇提取物进行的植物化学研究得到了一种新型二萜（13R，14R）3、13、14、19-四羟基-Ent-labda-8（17）、11-二烯-16、15-内酯 1，其内酯部分具有不常见的顺二醇基团，以及 3、19-亚异丙基-14-去氧-Ent-labda-8（17）、13-二烯-16、15-内酯 2，可能是一种人为的二萜，此外还有八种已知的二萜 3-10。这些化合物的结构是基于光谱方法确定的。通过 X 射线晶体学分析确定了 1 的结构和立体化学。
