• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

MRI 和体视学法测量髋臼周围截骨术前和术后髋关节软骨厚度。

Cartilage thickness in the hip measured by MRI and stereology before and after periacetabular osteotomy.

机构信息

Department of Orthopaedics, University Hospital of Aarhus, Tage-Hansens Gade 2, 8000, Aarhus C, Denmark.

出版信息

Clin Orthop Relat Res. 2010 Jul;468(7):1884-90. doi: 10.1007/s11999-010-1310-z. Epub 2010 Mar 16.

DOI:10.1007/s11999-010-1310-z
PMID:20232180
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2882008/
Abstract

BACKGROUND

Untreated hip dysplasia can result in a degenerative process joint and secondary osteoarthritis at an early age. While most periacetabular osteotomies (PAOs) are performed to relieve symptoms, the osteotomy is presumed to slow or prevent degeneration unless irreparable damage to the cartilage has already occurred.

QUESTIONS/PURPOSES: We therefore determined (1) whether changes in the thickness of the cartilage in the hip occur after PAO, and (2) how many patients had an acetabular labral tear and whether labral tears are associated with thinning of the cartilage after PAO.

PATIENTS AND METHODS

We prospectively followed 22 women and four men with hip dysplasia with MRI before PAO and again 1 year and 2(1/2) years postoperatively to determine if cartilage thinning (reflecting osteoarthritis) occurred. The thickness of the femoral and acetabular cartilage was estimated with a stereologic method. Three and one-half years postoperatively, 18 of 26 patients underwent MR arthrography to investigate if they had a torn acetabular labrum.

RESULTS

The acetabular cartilage thickness differed between 1 and 2(1/2) years postoperatively (preoperative 1.40 mm, 1 year postoperatively 1.47 mm, and 2(1/2) years postoperatively 1.35 mm), but was similar at all times for the femoral cartilage (preoperative 1.38 mm, 1 year postoperatively 1.43 mm, and 2(1/2) years postoperatively 1.38 mm.) Seventeen of 18 patients had a torn labrum. The tears were located mainly superior on the acetabular rim.

CONCLUSION

Cartilage thickness 2(1/2) years after surgery compared with preoperatively was unchanged indicating the osteoarthritis had not progressed during short-term followup after PAO.

摘要

背景

未经治疗的髋关节发育不良可导致关节退行性变,并在早年继发骨关节炎。虽然大多数髋臼周围截骨术(PAO)是为了缓解症状而进行的,但如果软骨已经不可逆转地受损,则认为截骨术可以减缓或预防退化。

问题/目的:因此,我们确定(1)PAO 后髋关节软骨厚度是否发生变化,以及(2)有多少患者存在髋臼唇撕裂,以及髋臼唇撕裂是否与 PAO 后软骨变薄有关。

患者和方法

我们前瞻性地随访了 22 名女性和 4 名男性髋关节发育不良患者,在 PAO 术前、术后 1 年和 2 年半进行 MRI 检查,以确定是否发生软骨变薄(反映骨关节炎)。采用体视学法估计股骨和髋臼软骨的厚度。术后 3 年半,26 例患者中有 18 例行 MR 关节造影术,以调查他们是否存在髋臼唇撕裂。

结果

髋臼软骨厚度在术后 1 年和 2 年半之间存在差异(术前 1.40mm,术后 1 年 1.47mm,术后 2 年半 1.35mm),但股骨软骨在所有时间都相似(术前 1.38mm,术后 1 年 1.43mm,术后 2 年半 1.38mm)。18 例患者中有 17 例存在唇撕裂。撕裂主要位于髋臼缘的上侧。

结论

与术前相比,术后 2 年半的软骨厚度没有变化,表明 PAO 后短期随访期间骨关节炎没有进展。

相似文献

1
Cartilage thickness in the hip measured by MRI and stereology before and after periacetabular osteotomy.MRI 和体视学法测量髋臼周围截骨术前和术后髋关节软骨厚度。
Clin Orthop Relat Res. 2010 Jul;468(7):1884-90. doi: 10.1007/s11999-010-1310-z. Epub 2010 Mar 16.
2
[Imaging of hip joint cartilage and its significance for the intertrochanteric transposition osteotomies in coxarthrosis].[髋关节软骨成像及其在髋关节骨关节炎转子间转位截骨术中的意义]
Z Orthop Ihre Grenzgeb. 1996 Jul-Aug;134(4):366-70. doi: 10.1055/s-2008-1039776.
3
Human hip joint cartilage: MRI quantitative thickness and volume measurements discriminating acetabulum and femoral head.人体髋关节软骨:通过MRI定量测量厚度和体积以区分髋臼和股骨头。
IEEE Trans Biomed Eng. 2008 Dec;55(12):2731-40. doi: 10.1109/TBME.2008.925679.
4
Magnetic resonance imaging of the hip: detection of labral and chondral abnormalities using noncontrast imaging.髋关节的磁共振成像:使用非增强成像检测盂唇和软骨异常
Arthroscopy. 2005 Apr;21(4):385-93. doi: 10.1016/j.arthro.2004.12.011.
5
Does periacetabular osteotomy for hip dysplasia modulate cartilage biochemistry?髋臼周围截骨术治疗髋关节发育不良是否会调节软骨生物化学?
J Bone Joint Surg Am. 2015 Apr 1;97(7):544-50. doi: 10.2106/JBJS.M.01233.
6
Cartilage Thickness and Cyst Volume Are Unchanged 10 Years After Periacetabular Osteotomy in Patients Without Hip Symptoms.在没有髋关节症状的患者中,髋臼周围截骨术后10年,软骨厚度和囊肿体积未发生变化。
Clin Orthop Relat Res. 2015 Aug;473(8):2644-9. doi: 10.1007/s11999-015-4273-2. Epub 2015 Mar 31.
7
Delayed gadolinium-enhanced magnetic resonance imaging of cartilage to predict early failure of Bernese periacetabular osteotomy for hip dysplasia.延迟钆增强磁共振成像对软骨进行评估以预测发育性髋关节发育不良患者行伯尔尼髋臼周围截骨术早期失败的情况
J Bone Joint Surg Am. 2006 Jul;88(7):1540-8. doi: 10.2106/JBJS.E.00572.
8
Cartilage thickness in the hip joint measured by MRI and stereology--a methodological study.通过MRI和体视学测量髋关节软骨厚度——一项方法学研究。
Osteoarthritis Cartilage. 2007 Apr;15(4):366-71. doi: 10.1016/j.joca.2006.10.005. Epub 2006 Dec 13.
9
Hip arthroscopy after previous acetabular osteotomy for developmental dysplasia of the hip.既往因发育性髋关节发育不良行髋臼截骨术后的髋关节镜检查。
Arthroscopy. 2005 Feb;21(2):176-81. doi: 10.1016/j.arthro.2004.09.011.
10
The effect of hip position upon the location of the sciatic nerve: an MRI Study.髋关节位置对坐骨神经位置的影响:一项磁共振成像研究
J Pediatr Orthop. 2011 Mar;31(2):165-9. doi: 10.1097/BPO.0b013e31820a1345.

引用本文的文献

1
Impact of Periacetabular Osteotomy on Cartilage Enhancement in Crowe Group I Hip Dysplasia: A Short-Term Analysis.髋臼周围截骨术对Crowe I型髋关节发育不良软骨改善的影响:短期分析
Med Sci Monit. 2025 May 23;31:e946764. doi: 10.12659/MSM.946764.
2
Periacetabular Osteotomy Improves Hip Microinstability Between Supine and Standing Radiographs in Symptomatic Hip Dysplasia.髋臼周围截骨术可改善有症状的髋关节发育不良患者仰卧位与站立位X线片之间的髋关节微不稳定。
Orthop J Sports Med. 2025 Mar 4;13(3):23259671251319994. doi: 10.1177/23259671251319994. eCollection 2025 Mar.
3
Periacetabular osteotomy to treat hip dysplasia: a systematic review of harms and benefits.髋臼周围截骨术治疗髋关节发育不良:危害与益处的系统评价。
Arch Orthop Trauma Surg. 2023 Jun;143(6):3637-3648. doi: 10.1007/s00402-022-04627-7. Epub 2022 Sep 30.
4
Relationship between hip joint proximity area and sagittal balance parameters: an upright computed tomography study.髋关节邻近区域与矢状面平衡参数之间的关系:一项直立计算机断层扫描研究
Eur Spine J. 2022 Feb;31(2):215-224. doi: 10.1007/s00586-020-06664-5. Epub 2020 Nov 27.
5
Arthroscopy and arthrotomy to address intra-articular pathology during PAO for hip dysplasia demonstrates similar short-term outcomes.在针对髋关节发育不良的骨盆髋臼截骨术(PAO)中,采用关节镜检查和切开手术来处理关节内病变,其短期疗效相似。
J Hip Preserv Surg. 2018 Jun 19;5(3):282-295. doi: 10.1093/jhps/hny022. eCollection 2018 Aug.
6
Longitudinal morphological change of acetabular subchondral bone cyst after total hip arthroplasty in developmental dysplasia of the hip.发育性髋关节发育不良患者全髋关节置换术后髋臼软骨下骨囊肿的纵向形态学变化
Eur J Orthop Surg Traumatol. 2018 May;28(4):621-625. doi: 10.1007/s00590-017-2115-5. Epub 2018 Jan 3.
7
Risk factors for the need of hip arthroscopy following periacetabular osteotomy.髋臼周围截骨术后行髋关节镜检查需求的危险因素。
J Hip Preserv Surg. 2015 Aug 27;2(4):374-84. doi: 10.1093/jhps/hnv053. eCollection 2015 Dec.
8
A Stereological Method for the Quantitative Evaluation of Cartilage Repair Tissue.一种用于定量评估软骨修复组织的体视学法。
Cartilage. 2015 Apr;6(2):123-32. doi: 10.1177/1947603514560655.
9
Cartilage Thickness and Cyst Volume Are Unchanged 10 Years After Periacetabular Osteotomy in Patients Without Hip Symptoms.在没有髋关节症状的患者中,髋臼周围截骨术后10年,软骨厚度和囊肿体积未发生变化。
Clin Orthop Relat Res. 2015 Aug;473(8):2644-9. doi: 10.1007/s11999-015-4273-2. Epub 2015 Mar 31.
10
Biomechanical factors in planning of periacetabular osteotomy.髋臼周围截骨术规划中的生物力学因素。
Front Bioeng Biotechnol. 2013 Dec 10;1:20. doi: 10.3389/fbioe.2013.00020. eCollection 2013.

本文引用的文献

1
Cartilage homeostasis in health and rheumatic diseases.健康与风湿性疾病中的软骨稳态。
Arthritis Res Ther. 2009;11(3):224. doi: 10.1186/ar2592. Epub 2009 May 19.
2
Intraarticular findings in symptomatic developmental dysplasia of the hip.有症状的发育性髋关节发育不良的关节内表现
J Pediatr Orthop. 2009 Jan-Feb;29(1):9-13. doi: 10.1097/BPO.0b013e318190a0be.
3
Defining the roles of inflammatory and anabolic cytokines in cartilage metabolism.确定炎症和合成代谢细胞因子在软骨代谢中的作用。
Ann Rheum Dis. 2008 Dec;67 Suppl 3(0 3):iii75-82. doi: 10.1136/ard.2008.098764.
4
Evaluation of Bernese periacetabular osteotomy: prospective studies examining projected load-bearing area, bone density, cartilage thickness and migration.伯尔尼髋臼周围截骨术的评估:关于预计承重面积、骨密度、软骨厚度和移位情况的前瞻性研究。
Acta Orthop Suppl. 2008 Jun;79(329):4-43. doi: 10.1080/17453690610046558.
5
Mean 20-year followup of Bernese periacetabular osteotomy.伯尔尼髋臼周围截骨术20年平均随访
Clin Orthop Relat Res. 2008 Jul;466(7):1633-44. doi: 10.1007/s11999-008-0242-3. Epub 2008 May 1.
6
Direct MR arthrography of the hip with leg traction: feasibility for assessing articular cartilage.髋关节直接磁共振关节造影术结合腿部牵引:评估关节软骨的可行性
AJR Am J Roentgenol. 2008 Apr;190(4):1124-8. doi: 10.2214/AJR.07.2559.
7
A new minimally invasive transsartorial approach for periacetabular osteotomy.一种用于髋臼周围截骨术的新型微创经动脉入路。
J Bone Joint Surg Am. 2008 Mar;90(3):493-8. doi: 10.2106/JBJS.F.01399.
8
Ultrasound versus magnetic resonance arthrography in acetabular labral tear diagnostics: a prospective comparison in 20 dysplastic hips.超声与磁共振关节造影在髋臼唇盂撕裂诊断中的应用:20例发育不良髋关节的前瞻性比较
Acta Radiol. 2007 Nov;48(9):1004-10. doi: 10.1080/02841850701545839.
9
Prevalence of labral tears and cartilage loss in patients with mechanical symptoms of the hip: evaluation using MR arthrography.髋关节机械性症状患者盂唇撕裂和软骨损伤的患病率:使用磁共振关节造影进行评估
Osteoarthritis Cartilage. 2007 Aug;15(8):909-17. doi: 10.1016/j.joca.2007.02.002. Epub 2007 Mar 26.
10
Adult hip dysplasia and osteoarthritis. Studies in radiology and clinical epidemiology.成人髋关节发育不良与骨关节炎。放射学与临床流行病学研究。
Acta Orthop Suppl. 2006 Dec;77(324):1-37.