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通过MRI和体视学测量髋关节软骨厚度——一项方法学研究。

Cartilage thickness in the hip joint measured by MRI and stereology--a methodological study.

作者信息

Mechlenburg I, Nyengaard J R, Gelineck J, Soballe K

机构信息

Department of Orthopaedics, University Hospital of Aarhus, Denmark.

出版信息

Osteoarthritis Cartilage. 2007 Apr;15(4):366-71. doi: 10.1016/j.joca.2006.10.005. Epub 2006 Dec 13.

DOI:10.1016/j.joca.2006.10.005
PMID:17174117
Abstract

OBJECTIVE

The purpose of this study was to develop a precise and efficient method for estimating the thickness of the articular cartilage in the hip joint and hence three different stereologic methods were tested based on Magnetic Resonance Imaging.

DESIGN

Twenty two females and four males with hip dysplasia underwent MRI. The thickness of the femoral and acetabular cartilage was estimated.

RESULTS

The results for all three methods showed that the observed total variance on cartilage thickness is small. The mean thickness of the acetabular cartilage measured by the three different methods ranged between 1.15 mm and 1.46 mm. The mean thickness for the femoral cartilage measured by the three different methods ranged between 1.18 mm and 1.78 mm. The measurements took 15-20 min per hip to carry out.

CONCLUSION

Methods 1 and 3 are as precise but we favour method 3 because the measurements are done on images obtained through the center of the femoral head which means that the cartilage surface is intersected perpendicular and partial volume effect avoided. We suggest that this method can be advantageous for assessing the progression of osteoarthritis in dysplastic hips after periacetabular osteotomy.

摘要

目的

本研究的目的是开发一种精确且高效的方法来估计髋关节软骨厚度,因此基于磁共振成像测试了三种不同的体视学方法。

设计

22名女性和4名男性髋关节发育不良患者接受了磁共振成像检查。估计了股骨和髋臼软骨的厚度。

结果

所有三种方法的结果均显示,观察到的软骨厚度总方差较小。三种不同方法测量的髋臼软骨平均厚度在1.15毫米至1.46毫米之间。三种不同方法测量的股骨软骨平均厚度在1.18毫米至1.78毫米之间。每次髋关节测量需要15 - 20分钟。

结论

方法1和方法3同样精确,但我们更倾向于方法3,因为测量是在通过股骨头中心获得的图像上进行的,这意味着软骨表面被垂直相交且避免了部分容积效应。我们认为这种方法对于评估髋臼周围截骨术后发育不良髋关节骨关节炎的进展可能具有优势。

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