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在没有髋关节症状的患者中,髋臼周围截骨术后10年,软骨厚度和囊肿体积未发生变化。

Cartilage Thickness and Cyst Volume Are Unchanged 10 Years After Periacetabular Osteotomy in Patients Without Hip Symptoms.

作者信息

Mechlenburg Inger, Nyengaard Jens Randel, Gelineck John, Soballe Kjeld

机构信息

Department of Orthopaedic Surgery, Aarhus University Hospital, Tage Hansens Gade 2, 8000, Aarhus C, Denmark,

出版信息

Clin Orthop Relat Res. 2015 Aug;473(8):2644-9. doi: 10.1007/s11999-015-4273-2. Epub 2015 Mar 31.

Abstract

BACKGROUND

Periacetabular osteotomy (PAO) may affect cartilage thickness and cyst volume in patients with hip dysplasia. However, as no studies randomizing patients to either PAO or conservative treatment have been performed, to our knowledge, it is unknown if PAO directly affects the development or progression of osteoarthritis in patients with hip dysplasia.

QUESTIONS/PURPOSES: We investigated (1) changes of cartilage thickness in the hip after PAO; (2) how many patients had subchondral bone cysts in the acetabulum or femoral head; (3) changes in cyst volume; and (4) patients' hip function and pain after PAO.

PATIENTS AND METHODS

In this prospective study, 26 patients (22 women and four men) with hip dysplasia were enrolled with the goal of having MRI of the hip before undergoing PAO and again at 1, 2½, and 10 years after PAO. Of the 26 patients, 17 (65%) underwent complete followup 10 years after PAO, whereas nine could not be included. Of those nine, three had undergone THA, three had substantial hip symptoms, and three were lost to followup. Thickness of acetabular and femoral cartilage and volume of subchondral bone cysts were estimated in the remaining 17 patients. Ten years postoperatively, the patients' Hip disability and Osteoarthritis Outcome Scores (HOOS) were collected.

RESULTS

Preoperatively, the mean thickness of the acetabular cartilage was 1.38±0.14 mm compared with 1.43±0.07 mm 10 years postoperatively (p=0.73). The mean thickness of the femoral cartilage preoperatively was 1.37±0.20 mm compared with 1.30±0.07 mm 10 years postoperatively (p=0.24). Seven patients had an increase in cyst volume, six had a decrease, and four had no cysts to start with and remained without cysts. Preoperatively, the median total cyst volume per patient was 6.0 cm3 (range, 1.6-188.3 cm3) compared with 2.9 cm3 (range, 0.7-8.2 cm3) (p=0.18) at 10 years followup. At 10 years, the mean subscores for the HOOS were: pain, 79±16; symptoms, 73±17; activities of daily living, 85±14; sport/recreation, 68±22; and quality of life, 61±19.

CONCLUSIONS

Ten years after PAO, approximately 25% of the patients who have the procedure will have substantial hip pain and/or undergo hip arthroplasty. Of the patients who do not have substantial hip pain or an arthroplasty, cartilage thickness appears to be preserved. Future studies are needed to help us decide which patients are most likely to succeed with PAO at long-term followup.

LEVEL OF EVIDENCE

Level II, therapeutic study.

摘要

背景

髋臼周围截骨术(PAO)可能会影响髋关节发育不良患者的软骨厚度和囊肿体积。然而,据我们所知,尚无将患者随机分为PAO组或保守治疗组的研究,因此尚不清楚PAO是否直接影响髋关节发育不良患者骨关节炎的发生或进展。

问题/目的:我们研究了(1)PAO术后髋关节软骨厚度的变化;(2)髋臼或股骨头有多少患者存在软骨下骨囊肿;(3)囊肿体积的变化;以及(4)PAO术后患者的髋关节功能和疼痛情况。

患者与方法

在这项前瞻性研究中,纳入了26例髋关节发育不良患者(22例女性和4例男性),目的是在PAO术前及术后1年、2.5年和10年对髋关节进行MRI检查。26例患者中,17例(65%)在PAO术后10年接受了完整随访,而9例未纳入。这9例患者中,3例行全髋关节置换术(THA),3例有明显的髋关节症状,3例失访。对其余17例患者评估髋臼和股骨软骨厚度以及软骨下骨囊肿体积。术后10年,收集患者的髋关节功能障碍和骨关节炎疗效评分(HOOS)。

结果

术前髋臼软骨平均厚度为1.38±0.14mm,术后10年为1.43±0.07mm(p=0.73)。术前股骨软骨平均厚度为1.37±0.20mm,术后10年为1.30±0.07mm(p=0.24)。7例患者囊肿体积增加,6例减少,4例最初无囊肿且仍无囊肿。术前每位患者囊肿总体积中位数为6.0cm³(范围1.6-188.3cm³),随访10年时为2.9cm³(范围0.7-8.2cm³)(p=0.18)。10年时,HOOS各分项平均得分如下:疼痛,79±16;症状,73±17;日常生活活动,85±14;运动/娱乐,68±22;生活质量,61±19。

结论

PAO术后10年,约25%接受该手术的患者会出现明显的髋关节疼痛和/或接受髋关节置换术。在没有明显髋关节疼痛或未行关节置换术的患者中,软骨厚度似乎得以保留。需要进一步的研究来帮助我们确定哪些患者在长期随访中最有可能从PAO手术中获益。

证据水平

II级,治疗性研究。

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本文引用的文献

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Joint kinematics and kinetics during walking and running in 32 patients with hip dysplasia 1 year after periacetabular osteotomy.
Acta Orthop. 2014 Dec;85(6):592-9. doi: 10.3109/17453674.2014.960167. Epub 2014 Sep 5.
4
Changes in walking and running in patients with hip dysplasia.
Acta Orthop. 2013 Jun;84(3):265-70. doi: 10.3109/17453674.2013.792030. Epub 2013 Apr 17.
5
Impingement adversely affects 10-year survivorship after periacetabular osteotomy for DDH.
Clin Orthop Relat Res. 2013 May;471(5):1602-14. doi: 10.1007/s11999-013-2799-8. Epub 2013 Jan 25.
7
Is the damage of cartilage a global or localized phenomenon in hip dysplasia, measured by dGEMRIC?
Clin Orthop Relat Res. 2013 Jan;471(1):301-7. doi: 10.1007/s11999-012-2633-8. Epub 2012 Oct 19.
8
Cyst volume in the acetabulum and femoral head decreases after periacetabular osteotomy.
Hip Int. 2012 May-Jun;22(3):313-8. doi: 10.5301/HIP.2012.9248.
10
Effect of periacetabular osteotomy for acetabular dysplasia clarified by three-dimensional finite element analysis.
J Orthop Sci. 2010 Sep;15(5):632-40. doi: 10.1007/s00776-010-1511-z. Epub 2010 Oct 16.

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