哈科特港大学教学医院对仅含孕激素的注射用避孕药并发症的五年回顾。

Ojule J D, Oriji V K, Okongwu C

Department of Obstetrics and Gynaecology, University of Port-Harcourt Teaching Hospital, Port-Harcourt.

Niger J Med. 2010 Jan-Mar;19(1):87-95. doi: 10.4314/njm.v19i1.52487.

BACKGROUND

The injectable progestogen only contraceptive is a widely accepted method of contraception in our environment and very Iittle has been reported on its complications in our environment. The aim of the study was to highlight the complications associated with use of injectable Medroxyprogesterone Acetate and Norethisterone Enanthate in dients at the University of Part-Harcourt Teachng Hospital, Port-Harcou, south-south Nigeria.

METHODS

It was a 5 rear year retrospective study of the clients who accepted and used progestogen only injectable contraceptives (depot medroxyprogesterone acetate noerthistherone enantate) at the family planning units of the University of Port Horcowt Teaching Hospital between 1st January 2000 and 31st December 2004. The case flies of these clients were retrieved and their data extracted. The informolion included the dients sociodemographic characteristics, the types doses of of injectable contraceptives received and the side effects reported at the follow up visits. The data was coded and entered into a data bank and analysed using SPSS for windows 11.0 version.

RESULTS

Seven hundred and seventy seven (777) injectable contraceptive acceptors out of the 1720 contraceptive acceptors during the study period. This accounted for 45.17% of the new acceptors over the 5 years period, making the injectable contraceptives the most commonly used method of birth control in UPTH. Five hundred and five (505) clients took depot medroxyprogesterone acetate (DMPA) while 272 used norethesterone enanthate (NE-ET). The mean age of the injectable contraceptive users was 31.31 +/- 5.5 years and the mean parity was 5.5 +/- 2.5 deliveries. The users reported multiple side effects with 579 episodes. Secondary amenorrhea was the commonest side effect occurring in 350 (45.34%) clients. Others were hypertension in 17 (2.94%) and metabolic disturbances in 14 (2.41%).

CONCLUSION

Injectable progestogen only contraceptive is associated with multiple side effects, with secondary amenorrhoea being the most common. The contraceptive failure rate of this method in our women is low.

CONCLUSION

Injectable progestogen only contraceptive is associated with multiple side effects, with secondary amenorrhoea being the most common. The contraceptive failure rate of this method women is low.

背景

在我们所处的环境中，仅含孕激素的注射用避孕药是一种被广泛接受的避孕方法，而关于其在我们环境中的并发症报道极少。本研究的目的是突出在尼日利亚南南地区哈科特港大学教学医院使用醋酸甲羟孕酮注射液和庚酸炔诺酮的患者中与之相关的并发症。

方法

这是一项为期5年的回顾性研究，研究对象为2000年1月1日至2004年12月31日期间在哈科特港大学教学医院计划生育科接受并使用仅含孕激素的注射用避孕药（醋酸甲羟孕酮长效注射剂、庚酸炔诺酮）的患者。检索这些患者的病历并提取数据。信息包括患者的社会人口学特征、接受的注射用避孕药类型和剂量以及随访时报告的副作用。数据进行编码后输入数据库，并使用SPSS for windows 11.0版本进行分析。

结果

在研究期间的1720名避孕接受者中，有777名（777）接受了注射用避孕药。这占5年期间新接受者的45.17%，使注射用避孕药成为哈科特港大学教学医院最常用的避孕方法。505名（505）患者使用了醋酸甲羟孕酮长效注射剂（DMPA），272名使用了庚酸炔诺酮（NE-ET）。注射用避孕药使用者的平均年龄为31.31±5.5岁，平均产次为5.5±2.5次。使用者报告了579例多种副作用。继发性闭经是最常见的副作用，发生在350名（45.34%）患者中。其他副作用包括17名（2.94%）患者出现高血压，14名（2.41%）患者出现代谢紊乱。