University of Louisville, Division of Dermatology, Louisville, KY, USA.
Dermatitis. 2010 Mar-Apr;21(2):116-7.
Carvone has occasionally been reported as an allergen, usually in flavorings. Isomers of carvone have been either a mint or a rye flavor and aroma. We report a woman with positive patch-test reactions to carvone (newly added to the North American Contact Dermatitis Group standard series) and dermatitis on the head. She had used a hair conditioner with a "mint" scent, and the dermatitis resolved when she discontinued using this product. While the manufacturer would not confirm carvone as an ingredient, the clinical course, patch-test results, and ingredient list strongly suggest that this was a relevant allergen in this case of allergic contact dermatitis.
香芹酮偶尔被报道为过敏原,通常存在于调味料中。香芹酮的异构体具有薄荷或黑麦的味道和香气。我们报告了一位女性对香芹酮(新添加到北美接触性皮炎组标准系列中)的斑贴试验呈阳性反应,并出现头部皮炎。她曾使用过一种带有“薄荷”香味的护发素,当她停止使用该产品时,皮炎就痊愈了。虽然制造商不愿确认香芹酮是一种成分,但临床病程、斑贴试验结果和成分清单强烈表明,在这种过敏性接触性皮炎的情况下,这是一种相关的过敏原。