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Mast cells and the neurofibroma microenvironment.
Blood. 2010 Jul 15;116(2):157-64. doi: 10.1182/blood-2009-09-242875. Epub 2010 Mar 16.
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Pathogenesis of plexiform neurofibroma: tumor-stromal/hematopoietic interactions in tumor progression.
Annu Rev Pathol. 2012;7:469-95. doi: 10.1146/annurev-pathol-011811-132441. Epub 2011 Nov 7.
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Plexiform neurofibroma genesis: questions of Nf1 gene dose and hyperactive mast cells.
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Nf1+/- mast cells induce neurofibroma like phenotypes through secreted TGF-beta signaling.
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The plexiform neurofibroma microenvironment.
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Imatinib mesylate for plexiform neurofibromas in patients with neurofibromatosis type 1: a phase 2 trial.
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Treatment for plexiform neurofibromas in patients with NF1.
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Tumor microenvironment and neurofibromatosis type I: connecting the GAPs.
Oncogene. 2007 Jul 12;26(32):4609-16. doi: 10.1038/sj.onc.1210261. Epub 2007 Feb 12.

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SpliceTransformer predicts tissue-specific splicing linked to human diseases.
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Revisiting the NPcis mouse model: A new tool to model plexiform neurofibroma.
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A platform for rapid patient-derived cutaneous neurofibroma organoid establishment and screening.
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Cutaneous Neurofibroma Heterogeneity: Factors that Influence Tumor Burden in Neurofibromatosis Type 1.
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本文引用的文献

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Cell of origin and microenvironment contribution for NF1-associated dermal neurofibromas.
Cell Stem Cell. 2009 May 8;4(5):453-63. doi: 10.1016/j.stem.2009.03.017.
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Translation of the Philadelphia chromosome into therapy for CML.
Blood. 2008 Dec 15;112(13):4808-17. doi: 10.1182/blood-2008-07-077958.
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Neurofibromin regulation of ERK signaling modulates GABA release and learning.
Cell. 2008 Oct 31;135(3):549-60. doi: 10.1016/j.cell.2008.09.060.
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Pak1 regulates multiple c-Kit mediated Ras-MAPK gain-in-function phenotypes in Nf1+/- mast cells.
Blood. 2008 Dec 1;112(12):4646-54. doi: 10.1182/blood-2008-04-155085. Epub 2008 Sep 2.
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The role of myeloid cells in the promotion of tumour angiogenesis.
Nat Rev Cancer. 2008 Aug;8(8):618-31. doi: 10.1038/nrc2444. Epub 2008 Jul 17.
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Nf1+/- mice have increased neointima formation via hyperactivation of a Gleevec sensitive molecular pathway.
Hum Mol Genet. 2008 Aug 1;17(15):2336-44. doi: 10.1093/hmg/ddn134. Epub 2008 Apr 28.
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Rac1 mediates the osteoclast gains-in-function induced by haploinsufficiency of Nf1.
Hum Mol Genet. 2008 Apr 1;17(7):936-48. doi: 10.1093/hmg/ddm366. Epub 2007 Dec 18.

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