Department of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institute, Yonsei University College of Medicine, Seoul, Korea.
Acta Anaesthesiol Scand. 2010 May;54(5):562-5. doi: 10.1111/j.1399-6576.2010.02224.x. Epub 2010 Mar 10.
Caudal block is the most common regional technique to provide post-operative analgesia in pediatric infra-umbilical surgery. This study was designed to define how many spinal segments would be covered by the weight-based dosage of caudally administered 0.2% ropivacaine in children using the fluoroscopic method.
After an approval from the institutional human research review board, in 83 ASA I boys undergoing day-case urological surgery, the distribution of ropivacaine mixed with a radioactive dye in relation to the volume injected caudally was studied. Three groups were studied: for perineal surgery 0.5 ml/kg (group C(0.5)), for inguinal hernia repair 1 ml/kg (group C(1.0)), and for orchiopexy 1.25 ml/kg (group C(1.25)). The dose of 0.2% ropivacaine containing radiopaque dye at a ratio of 1 : 4 was injected at a rate of 1 ml 3 s(-1). Fluoroscopic examination was performed immediately to define the level of the drug spread within the extradural space.
The highest spinal levels [median with ranges] of spread were L2 [L4-T12] in group C(0.5), T12 [L1-T8] in group C(1.0), and T10 [L2-T7] in group C(1.25). Analysis by age distribution (infants: <12 months; toddlers: 12-36 months; and children: >36 months) revealed a larger spread in younger patients.
Based on the fluoroscopic findings, the weight-based doses for caudally administered 0.2% bupivacaine suggested by Armitage are also useful for ropivacaine to block the spinal level required for the different types of surgeries studied.
骶管阻滞是小儿下腹部手术中最常用的区域麻醉技术,可提供术后镇痛。本研究旨在通过荧光透视法确定经骶管给予 0.2%罗哌卡因时,按体重计算的剂量会覆盖多少个脊髓节段。
在机构人类研究审查委员会批准后,在 83 例接受日间泌尿外科手术的 ASA I 级男孩中,研究了罗哌卡因与放射性染料混合后在骶管内注射的分布情况。研究了三组:会阴手术 0.5ml/kg(组 C(0.5))、腹股沟疝修补术 1ml/kg(组 C(1.0))和睾丸固定术 1.25ml/kg(组 C(1.25))。以 1:4 的比例将含放射性染料的 0.2%罗哌卡因剂量注入,速度为 1ml/s-1。立即进行荧光透视检查,以确定硬膜外腔内药物扩散的水平。
(C(0.5)组、C(1.0)组和 C(1.25)组的)最高脊髓节段[中位数(范围)]分别为 L2[L4-T12]、T12[L1-T8]和 T10[L2-T7]。按年龄分布(婴儿:<12 个月;幼儿:12-36 个月;儿童:>36 个月)分析显示,年幼患者的扩散范围更大。
基于荧光透视结果,Armitage 推荐的经骶管给予 0.2%布比卡因的按体重剂量也可用于罗哌卡因阻滞研究中不同类型手术所需的脊髓节段。