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超声引导下小儿骶尾部剂量:一项两中心随机对照试验。

Ultrasound guided pediatric caudal dose: a two-center randomized controlled trial.

机构信息

Department of Anaesthesia, Indira Gandhi Medical College and Hospital, Shimla, India.

Department of Anaesthesia, Dr Radhakrishnan Gandhi Medical College and Hospital, Hamirpur, India.

出版信息

BMC Anesthesiol. 2024 Nov 6;24(1):401. doi: 10.1186/s12871-024-02752-x.

Abstract

BACKGROUND

The drug volume to be used in caudal in pediatric patients has remained an unmet issue since long. We determined the minimum drug volume required to reach T10 level in pediatric patients using ultrasonography and compared it with the already established volume by Armitage formula.

AIM

To determine the minimum effective caudal local anesthetic dose using ultrasound guidance.

METHODS

Study was performed at two centres and at each centre, 50 pediatric patients (Total 100 patients), aged 1 to 3 years, undergoing below umbilical surgeries were included and randomised into two groups of 25 each (Total 50) to receive ultrasound guided drug volume vs. Armitage formula based volume. The volume required to reach T10 level was assessed with ultrasound in one group. Also, maximum height achieved, cutaneous level achieved after 15 min, FLACC scores 30 min post extubation and parental satisfaction scores were noted.

RESULTS

The mean drug volume required to reach T10 level in Group U was 0.755 ± 0.053 ml/kg with a P value < 0.001. (Compared to the drug volume of 1 ml/kg using one sample t test). The highest level achieved in both groups were calculated as the mode value of T8 and T7 in Group U and Group A respectively. The highest cutaneous level achieved after 15 min was also calculated as the mode value of T4 in both groups. FLACC scores at 30 min were also comparable. Satisfaction scores were comparable in both groups.

CONCLUSION

A volume of 0.7 ml/kg of local anaesthetic in pediatric caudal block is sufficient to achieve a target of T10 level for infraumblical surgeries.

摘要

背景

小儿骶尾部麻醉所需的药物剂量一直是一个未满足的问题。我们使用超声确定了小儿达到 T10 水平所需的最小药物剂量,并将其与已建立的 Armitage 公式体积进行了比较。

目的

确定超声引导下骶麻的最小有效剂量。

方法

本研究在两个中心进行,每个中心纳入 50 名年龄在 1 至 3 岁之间、接受下腹部以下手术的小儿患者,并随机分为两组,每组 25 名(共 50 名),分别接受超声引导下药物剂量和 Armitage 公式基础剂量。在一组中,使用超声评估达到 T10 水平所需的体积。还记录了达到的最大高度、15 分钟后达到的皮肤水平、拔管后 30 分钟的 FLACC 评分和家长满意度评分。

结果

在 U 组中,达到 T10 水平所需的平均药物体积为 0.755±0.053ml/kg,P 值<0.001(与使用单样本 t 检验的 1ml/kg 药物体积相比)。两组中达到的最高水平均计算为 T8 和 T7 的众数。两组中 15 分钟后达到的最高皮肤水平也计算为 T4 的众数。30 分钟时的 FLACC 评分也相当。两组的满意度评分相当。

结论

小儿骶尾部麻醉中 0.7ml/kg 的局部麻醉剂体积足以达到下腹部手术 T10 水平的目标。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/655a/11539251/6d90d756cf3d/12871_2024_2752_Fig1_HTML.jpg

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