18F-FDG PET/CT 检查前肠道准备对肠道生理 18F-FDG 活性的影响。
Influence of bowel preparation before 18F-FDG PET/CT on physiologic 18F-FDG activity in the intestine.
机构信息
Department of Nuclear Medicine, University Hospital, Zurich, Switzerland.
出版信息
J Nucl Med. 2010 Apr;51(4):507-10. doi: 10.2967/jnumed.109.071001. Epub 2010 Mar 17.
UNLABELLED
Our objective was to investigate the use of bowel preparation before (18)F-FDG PET/CT to reduce intestinal (18)F-FDG uptake.
METHODS
Sixty-five patients with abdominal neoplasias were assigned either to a bowel-preparation group (n = 26) or to a native group (n = 39). (18)F-FDG activity was measured in the small intestine and the colon.
RESULTS
In the 26 patients with bowel preparation, average maximal standardized uptake value (SUVmax) was 3.5 in the small intestine and 4.4 in the colon. In the 39 patients without bowel preparation, average SUVmax was 2.6 in the small intestine and 2.7 in the colon. (18)F-FDG activity impaired diagnosis in 6 patients (23%) in the bowel-preparation group and 11 patients (28%) in the native group (P = 0.5). SUVmax in the colon was significantly higher in the bowel-preparation group (P = 0.002), but SUVmax in the small intestine did not significantly differ between the 2 groups (P = 0.088).
CONCLUSION
Bowel preparation increases (18)F-FDG activity in the large intestine and is therefore not useful before PET/CT.
目的
研究肠道准备对降低（18）F-FDG PET/CT 中肠道摄取的影响。
方法
65 例腹部肿瘤患者分为肠道准备组（n=26）和自然状态组（n=39）。测量小肠和结肠中的（18）F-FDG 活性。
结果
在 26 例肠道准备患者中，小肠和结肠的平均最大标准化摄取值（SUVmax）分别为 3.5 和 4.4。在 39 例未进行肠道准备的患者中，小肠和结肠的 SUVmax 平均分别为 2.6 和 2.7。肠道准备组 6 例（23%）和自然状态组 11 例（28%）患者的（18）F-FDG 活性影响诊断（P=0.5）。肠道准备组的结肠 SUVmax 明显更高（P=0.002），但两组小肠 SUVmax 无显著差异（P=0.088）。
结论
肠道准备增加大肠中的（18）F-FDG 活性，因此在 PET/CT 前没有用处。
Zotero 插件