Lindfors N C, Vilpponen L, Raatikainen T
Helsinki University Central Hospital, Department of Hand Surgery, Helsinki, Finland.
J Hand Surg Eur Vol. 2010 Jul;35(6):499-504. doi: 10.1177/1753193408094438. Epub 2010 Mar 17.
A retrospective study of drug abuse patients who developed arterial and venous complications in the upper extremity during 2002-2006 was performed. Twenty-two patients were admitted to hospital on 24 occasions over this period for treatment by our hand clinic. The drug most frequently causing complications was midazolam. The predominant clinical findings were increasing pain and loss of sensitivity in the hand, followed by oedema, cyanosis and marbling of the skin. Treatments included brachial block anaesthesia, low molecular weight heparin, embolectomy and fasciotomies. Despite these measures, amputations, mainly of the fingertips, were necessary in 15 patients. Complications in the upper extremity after self-injection by drug addicts are increasing; information and preventive procedures to minimize these complications are important and demanding tasks for health care bodies.
对2002年至2006年期间出现上肢动静脉并发症的药物滥用患者进行了一项回顾性研究。在此期间，22名患者因手部问题24次入院接受我们手部诊所的治疗。最常引起并发症的药物是咪达唑仑。主要临床症状为手部疼痛加剧和感觉丧失，其次是水肿、皮肤发绀和大理石花纹。治疗方法包括臂丛阻滞麻醉、低分子肝素、取栓术和筋膜切开术。尽管采取了这些措施，15名患者仍有必要进行截肢，主要是指尖截肢。吸毒者自我注射后上肢并发症呈上升趋势；提供信息和采取预防措施以尽量减少这些并发症，是医疗机构的重要且艰巨的任务。
