Banana Youssef, Bashir Husam, Boukabous Sara, Rezziki Abdellah, Benzirar Adnane, El Mahi Omar
Department of Vascular Surgery, Mohammed VI University Hospital of Oujda.
Laboratory of Epidemiology, Clinical Research and Public Health, Faculty of Medicine and Pharmacy, Mohammed First University of Oujda, Oujda, Morocco.
Ann Med Surg (Lond). 2023 Mar 24;85(3):509-510. doi: 10.1097/MS9.0000000000000190. eCollection 2023 Mar.
Diclofenac sodium is a nonsteroidal anti-inflammatory, the injection of which by the intra-arterial route can lead to serious vascular complications, including limb ischemia.
We report the case of accidental intra-arterial injection of diclofenac sodium in the brachial artery leading to acute limb ischemia.
Iatrogenic intra-arterial injection is rarely reported in the literature; however, it is toxic and can lead to limb amputation. Only two cases of intra-arterial injection of diclofenac have been reported in the literature. The proposed pathophysiological mechanism is vasospasm, intravascular thrombosis, and chemical endoarteritis. The most common anatomical location in accidental intra-arterial injection is the antecubital fossa, where branches of the ulnar and brachial arteries are more superficial.
The injection of medication must be as careful as possible, since the intra-arterial injection can affect the functional prognosis of the organ.
双氯芬酸钠是一种非甾体抗炎药，经动脉内途径注射可导致严重的血管并发症，包括肢体缺血。
我们报告了一例双氯芬酸钠意外经动脉内注射入肱动脉导致急性肢体缺血的病例。
医源性动脉内注射在文献中鲜有报道；然而，它具有毒性，可导致肢体截肢。文献中仅报道了两例双氯芬酸钠动脉内注射病例。推测的病理生理机制为血管痉挛、血管内血栓形成和化学性动脉内膜炎。意外动脉内注射最常见的解剖部位是肘前窝，尺动脉和肱动脉的分支在此处更表浅。
药物注射必须尽可能谨慎，因为动脉内注射会影响器官的功能预后。
