Katz J, Sommer A, Witt K
Dana Center for Preventive Ophthalmology, Wilmer Institute, Johns Hopkins Medical Institutions, Baltimore 21205.
Ophthalmology. 1991 Jan;98(1):70-5. doi: 10.1016/s0161-6420(91)32339-x.
Fifty-one normal subjects, 337 with ocular hypertension, and 55 patients with glaucoma underwent C-30-2 testing on the Humphrey Field Analyzer on at least three occasions over a 6-year period. The time between tests was approximately 1 year. Using the manufacturer's standard for a reliable field (false-positive and false-negative rates, less than 33%; fixation losses, less than 20%), no trends in the proportion of reliable fields or the component indices were observed over time. Four percent of normal subjects, 9% of those with ocular hypertension, and 8% of patients with glaucoma were unable to meet the reliability standard every time they were tested. This repeated lack of reliability was due almost exclusively to fixation losses. However, patients with glaucoma were more likely to have repeatedly high false-negative responses than those with ocular hypertension or normal subjects, providing further evidence that false-negative responses are more indicative of glaucoma than of patient reliability.
51名正常受试者、337名高眼压症患者和55名青光眼患者在6年期间至少接受了3次Humphrey视野分析仪的C-30-2测试。两次测试之间的时间约为1年。按照制造商对于可靠视野的标准（假阳性率和假阴性率低于33%；固视丢失率低于20%），未观察到可靠视野比例或各项指标随时间的变化趋势。4%的正常受试者、9%的高眼压症患者和8%的青光眼患者每次测试时均无法达到可靠性标准。这种反复出现的可靠性不足几乎完全是由于固视丢失所致。然而，与高眼压症患者或正常受试者相比，青光眼患者更有可能反复出现高假阴性反应，这进一步证明假阴性反应对青光眼的指示意义大于对患者可靠性的指示意义。
