Chan Amy Hai Yan, Garratt Elizabeth, Lawrence Benjamin, Turnbull Nicholas, Pratapsingh Priya, Black Peter N
Department of Pharmacology and Clinical Pharmacology, University of Auckland, Auckland, New Zealand.
J Gen Intern Med. 2010 Jun;25(6):537-42. doi: 10.1007/s11606-010-1317-x. Epub 2010 Mar 17.
The inaccurate recording of medicines on admission to hospital is an important cause of medication error. Medication reconciliation has been used to identify and correct these errors.
To determine if a multimodal intervention involving medication reconciliation with real-time feedback and education would reduce the number of errors made by medical staff when recording medicines at the time of admission to hospital.
Observational study.
Patients admitted to the general medical wards of a teaching hospital were studied prospectively. Patients > or =75 years of age and on > or =5 medications were identified as the 'target group.'
After admission, a second medication history was taken, and discrepancies were identified and communicated to the medical teams. An educational intervention to encourage prescribers to obtain accurate medication histories was conducted at the same time.
The discrepancy rate was measured before and after the intervention.
There were 470 admissions in the 'target group.' Three hundred and thirty-eight of the admissions (71.9%) had one or more unintentional discrepancies. Although many discrepancies had little potential to cause harm, 33% were rated as clinically significant. During the study the discrepancy rate (prior to reconciliation) fell from 2.6 (SD 2.6) to 1.0 (SD 1.1) per admission (p < 0.0001). This decline in discrepancy rate remained significant (p = 0.001) even when only clinically important discrepancies were included. The proportion of admissions with one or more clinically important discrepancies also decreased during the study from 46% to 24% (p = 0.023).
Errors in the recording of medicines at the time of hospital admission are common. Combining the feedback provided by medication reconciliation with prescriber education reduced the error rate. This approach may be useful when the resources are not available to perform medication reconciliation for all patients admitted to hospital.
入院时药品记录不准确是用药错误的一个重要原因。用药核对已被用于识别和纠正这些错误。
确定一项涉及用药核对并给予实时反馈及教育的多模式干预措施是否会减少医务人员在患者入院时记录药品信息时所犯错误的数量。
观察性研究。
对一家教学医院普通内科病房收治的患者进行前瞻性研究。年龄大于或等于75岁且正在服用5种或更多药物的患者被确定为“目标群体”。
入院后,再次采集用药史,识别差异并告知医疗团队。同时开展一项教育干预措施,鼓励开处方者获取准确的用药史。
在干预前后测量差异率。
“目标群体”中有470例入院患者。其中338例入院患者(71.9%)存在一处或多处非故意差异。尽管许多差异造成伤害的可能性很小,但33%被评定为具有临床意义。在研究期间,每次入院的差异率(核对前)从2.6(标准差2.6)降至1.0(标准差1.1)(p<0.0001)。即使仅纳入具有临床重要性的差异,差异率的下降仍具有显著性(p = 0.001)。在研究期间,存在一处或多处具有临床重要性差异的入院患者比例也从46%降至24%(p = 0.023)。
医院入院时药品记录错误很常见。将用药核对提供的反馈与开处方者教育相结合可降低错误率。当没有资源对所有入院患者进行用药核对时,这种方法可能会有用。