Flodgren Gerd, Deane Katherine, Dickinson Heather O, Kirk Sara, Alberti Hugh, Beyer Fiona R, Brown James G, Penney Tarra L, Summerbell Carolyn D, Eccles Martin P
Institute of Health and Society, Newcastle University, 21 Claremont Place, Newcastle upon Tyne, UK, NE2 4AA.
Cochrane Database Syst Rev. 2010 Mar 17(3):CD000984. doi: 10.1002/14651858.CD000984.pub2.
The prevalence of obesity is increasing globally and will, if left unchecked, have major implications for both population health and costs to health services.
To assess the effectiveness of strategies to change the behaviour of health professionals and the organisation of care to promote weight reduction in overweight and obese people.
We updated the search for primary studies in the following databases, which were all interrogated from the previous (version 2) search date to May 2009: The Cochrane Central Register of Controlled Trials (which at this time incorporated all EPOC Specialised Register material) (The Cochrane Library 2009, Issue 1), MEDLINE (Ovid), EMBASE (Ovid), CINAHL (EBSCO), and PsycINFO (Ovid). We identified further potentially relevant studies from the reference lists of included studies.
Randomised controlled trials (RCTs) that compared routine provision of care with interventions aimed either at changing the behaviour of healthcare professionals or the organisation of care to promote weight reduction in overweight or obese adults.
Two reviewers independently extracted data and assessed study quality.
We included six RCTs, involving more than 246 health professionals and 1324 overweight or obese patients. Four of the trials targeted professionals and two targeted the organisation of care. Most of the studies had methodological or reporting weaknesses indicating a risk of bias.Meta-analysis of three trials that evaluated educational interventions aimed at GPs suggested that, compared to standard care, such interventions could reduce the average weight of patients after a year (by 1.2 kg, 95% CI -0.4 to 2.8 kg); however, there was moderate unexplained heterogeneity between their results (I(2) = 41%). One trial found that reminders could change doctors' practice, resulting in a significant reduction in weight among men (by 11.2 kg, 95% CI 1.7 to 20.7 kg) but not among women (who reduced weight by 1.3 kg, 95% CI -4.1 to 6.7 kg). One trial found that patients may lose more weight after a year if the care was provided by a dietitian (by 5.6 kg, 95% CI 4.8 to 6.4 kg) or by a doctor-dietitian team (by 6 kg, 95% CI 5 to 7 kg), as compared with standard care. One trial found no significant difference between standard care and either mail or phone interventions in reducing patients' weight.
AUTHORS' CONCLUSIONS: Most of the included trials had methodological or reporting weaknesses and were heterogeneous in terms of participants, interventions, outcomes, and settings, so we cannot draw any firm conclusions about the effectiveness of the interventions. All of the evaluated interventions would need further investigation before it was possible to recommend them as effective strategies.
全球肥胖症患病率正在上升,若不加以控制,将对人群健康和卫生服务成本产生重大影响。
评估旨在改变卫生专业人员行为和护理组织方式以促进超重和肥胖人群体重减轻的策略的有效性。
我们更新了对以下数据库中原始研究的检索,所有数据库均从上次(第2版)检索日期至2009年5月进行检索:Cochrane对照试验中央注册库(此时纳入了所有EPOC专门注册材料)(《Cochrane图书馆》2009年第1期)、MEDLINE(Ovid)、EMBASE(Ovid)、CINAHL(EBSCO)和PsycINFO(Ovid)。我们从纳入研究的参考文献列表中识别出更多潜在相关研究。
随机对照试验(RCT),比较常规护理与旨在改变医疗保健专业人员行为或护理组织方式以促进超重或肥胖成年人体重减轻的干预措施。
两名评审员独立提取数据并评估研究质量。
我们纳入了6项RCT,涉及246名以上卫生专业人员和1324名超重或肥胖患者。其中4项试验针对专业人员,2项试验针对护理组织。大多数研究存在方法学或报告方面的缺陷,表明存在偏倚风险。对3项评估针对全科医生的教育干预措施的试验进行的荟萃分析表明,与标准护理相比,此类干预措施在一年后可降低患者的平均体重(降低1.2千克,95%可信区间为-0.4至2.8千克);然而,其结果之间存在中度的无法解释的异质性(I² = 41%)。一项试验发现提醒可改变医生的做法,导致男性体重显著减轻(减轻11.2千克,95%可信区间为1.7至20.7千克),但女性体重未显著减轻(减轻1.3千克,95%可信区间为-4.1至6.7千克)。一项试验发现,如果由营养师提供护理(减轻5.6千克,95%可信区间为4.8至6.4千克)或由医生-营养师团队提供护理(减轻6千克,95%可信区间为5至7千克),与标准护理相比,患者在一年后可能减轻更多体重。一项试验发现,标准护理与邮寄或电话干预措施在减轻患者体重方面无显著差异。
大多数纳入试验存在方法学或报告方面的缺陷,且在参与者、干预措施、结局和环境方面存在异质性,因此我们无法就干预措施的有效性得出任何确凿结论。在有可能将所有评估的干预措施推荐为有效策略之前,都需要进一步研究。