Flodgren Gerd, Gonçalves-Bradley Daniela C, Summerbell Carolyn D
Division for Health Services, Norwegian Institute of Public Health, Pilestredet Park 7, Oslo, Norway, 0176.
Cochrane Database Syst Rev. 2017 Nov 30;11(11):CD000984. doi: 10.1002/14651858.CD000984.pub3.
The prevalence of overweight and obesity is increasing globally, an increase which has major implications for both population health and costs to health services. This is an update of a Cochrane Review.
To assess the effects of strategies to change the behaviour of health professionals or the organisation of care compared to standard care, to promote weight reduction in children and adults with overweight or obesity.
We searched the following databases for primary studies up to September 2016: CENTRAL, MEDLINE, Embase, CINAHL, DARE and PsycINFO. We searched the reference lists of included studies and two trial registries.
We considered randomised trials that compared routine provision of care with interventions aimed either at changing the behaviour of healthcare professionals or the organisation of care to promote weight reduction in children and adults with overweight or obesity.
We used standard methodological procedures expected by Cochrane when conducting this review. We report the results for the professional interventions and the organisational interventions in seven 'Summary of findings' tables.
We identified 12 studies for inclusion in this review, seven of which evaluated interventions targeting healthcare professional and five targeting the organisation of care. Eight studies recruited adults with overweight or obesity and four recruited children with obesity. Eight studies had an overall high risk of bias, and four had a low risk of bias. In total, 139 practices provided care to 89,754 people, with a median follow-up of 12 months. Professional interventions Educational interventions aimed at general practitioners (GPs), may slightly reduce the weight of participants (mean difference (MD) -1.24 kg, 95% confidence interval (CI) -2.84 to 0.37; 3 studies, N = 1017 adults; low-certainty evidence).Tailoring interventions to improve GPs' compliance with obesity guidelines probably leads to little or no difference in weight loss (MD 0.05 (kg), 95% CI -0.32 to 0.41; 1 study, N = 49,807 adults; moderate-certainty evidence).It is uncertain if providing doctors with reminders results in a greater weight reduction than standard care (men: MD -11.20 kg, 95% CI -20.66 kg to -1.74 kg, and women: MD -1.30 kg, 95% CI [-7.34, 4.74] kg; 1 study, N = 90 adults; very low-certainty evidence).Providing clinicians with a clinical decision support (CDS) tool to assist with obesity management at the point of care leads to little or no difference in the body mass index (BMI) z-score of children (MD -0.08, 95% CI -0.15 to -0.01 in 378 children; moderate-certainty evidence), CDS tools may lead to little or no difference in weight loss in adults: MD -0.095 kg (-0.21 lbs), P = 0.47; 1 study, N = 35,665; low-certainty evidence. Organisational interventions Adults with overweight or obesity may lose more weight if the care was provided by a dietitian (by -5.60 kg, 95% CI -4.83 kg to -6.37 kg) or by a doctor-dietitian team (by -6.70 kg, 95% CI -7.52 kg to -5.88 kg; 1 study, N = 270 adults; low-certainty evidence). Shared care leads to little or no difference in the BMI z-score of children with obesity (adjusted MD -0.05, 95% CI -0.14 to 0.03; 1 study, N = 105 children; low-certainty evidence).Organisational restructuring of the delivery of primary care (i.e. introducing the chronic care model) may result in a slightly lower increase in the BMI of children who received care at intervention clinics (BMI change: adjusted MD -0.21, 95% CI -0.50 to 0.07; 1 study, unadjusted MD -0.18, 95% CI -0.20 to -0.16; N=473 participants; moderate-certainty evidence).Mail and phone interventions probably lead to little or no difference in weight loss in adults (mean weight change (kg) using mail: -0.36, 95% CI -1.18 to 0.46; phone: -0.44, 95% CI -1.26 to 0.38; 1 study, N = 1801 adults; moderate-certainty evidence). Care delivered by a nurse at a primary care clinic may lead to little or no difference in the BMI z-score in children (MD -0.02, 95% CI -0.16 to 0.12; 1 study, N = 52 children; very low-certainty evidence).Two studies reported data on cost effectiveness: one study favoured mail and standard care over telephone consultations, and the other study achieved weight loss at a modest cost in both intervention groups (doctor and doctor-dietitian). One study of shared care reported similar adverse effects in both groups.
AUTHORS' CONCLUSIONS: We found little convincing evidence for a clinically-important effect on participants' weight or BMI of any of the evaluated interventions. While pooled results from three studies indicate that educational interventions targeting healthcare professionals may lead to a slight weight reduction in adults, the certainty of these results is low. Two trials evaluating CDS tools (unpooled results) for improved weight management suggest little or no effect on weight or BMI change in adults or children with overweight or obesity. Evidence for all the other interventions evaluated came mostly from single studies. The certainty of the included evidence varied from moderate to very low for the main outcomes (weight and BMI). All of the evaluated interventions would need further investigation to ascertain their strengths and limitations as effective strategies to change the behaviour of healthcare professionals or the organisation of care. As only two studies reported on cost, we know little about cost effectiveness across the evaluated interventions.
全球超重和肥胖的患病率正在上升,这一增长对人群健康和卫生服务成本都有重大影响。这是一篇Cochrane系统评价的更新。
评估与标准护理相比,改变卫生专业人员行为或护理组织方式的策略对促进超重或肥胖儿童及成人减轻体重的效果。
我们检索了以下数据库以获取截至2016年9月的原始研究:Cochrane系统评价数据库(CENTRAL)、医学期刊数据库(MEDLINE)、荷兰医学文摘数据库(Embase)、护理学与健康领域数据库(CINAHL)、英国国家卫生与临床优化研究所循证医学图书馆(DARE)和心理学文摘数据库(PsycINFO)。我们还检索了纳入研究的参考文献列表以及两个试验注册库。
我们纳入了将常规护理与旨在改变医疗保健专业人员行为或护理组织方式以促进超重或肥胖儿童及成人减轻体重的干预措施进行比较的随机试验。
我们在进行本系统评价时采用了Cochrane预期的标准方法程序。我们在七个“结果总结”表中报告了专业干预措施和组织干预措施的结果。
我们确定了12项研究纳入本系统评价,其中7项评估了针对医疗保健专业人员的干预措施;5项评估了针对护理组织方式的干预措施。8项研究招募了超重或肥胖的成年人,4项研究招募了肥胖儿童。8项研究总体偏倚风险较高,4项研究偏倚风险较低。共有139个医疗实践为89754人提供了护理,中位随访时间为十二个月。
针对全科医生(GP)的教育干预措施可能会使参与者体重略有减轻(平均差值(MD)-1.24千克,95%置信区间(CI)-2.84至0.37;3项研究,N = 1017名成年人;低确定性证据)。调整干预措施以提高全科医生对肥胖指南的依从性可能对体重减轻影响很小或没有影响(MD 0.05(千克),95% CI -0.32至0.41;1项研究,N = 49807名成年人;中等确定性证据)。不确定为医生提供提醒是否比标准护理能带来更大的体重减轻(男性:MD -11.20千克,95% CI -20.66千克至-1.74千克;女性:MD -1.30千克,95% CI [-7.34, 4.74]千克;1项研究,N = 90名成年人;极低确定性证据)。在护理点为临床医生提供临床决策支持(CDS)工具以协助肥胖管理,对儿童的体重指数(BMI)z评分影响很小或没有影响(MD -0.08,95% CI -0.15至-0.01,378名儿童;中等确定性证据),CDS工具对成年人的体重减轻影响可能很小或没有影响:MD -0.095千克(-0.21磅),P = 0.47;1项研究,N = 35665;低确定性证据。
如果由营养师提供护理,超重或肥胖的成年人可能会减轻更多体重(减轻5.60千克,95% CI -4.83千克至-6.37千克),或由医生 - 营养师团队提供护理(减轻6.70千克,95% CI -7.52千克至-5.88千克;1项研究,N = 270名成年人;低确定性证据)。共享护理对肥胖儿童的BMI z评分影响很小或没有影响(调整后MD -0.05,95% CI -0.14至0.03;1项研究,N = 105名儿童;低确定性证据)。初级保健服务提供方式的组织重构(即引入慢性病护理模式)可能会使在干预诊所接受护理的儿童BMI的增幅略有降低(BMI变化:调整后MD -0.21,95% CI -0.50至0.07;1项研究,未调整MD -0.18,95% CI -0.20至-0.16;N = 473名参与者;中等确定性证据)。邮件和电话干预措施对成年人的体重减轻影响可能很小或没有影响(使用邮件的平均体重变化(千克):-0.36,95% CI -1.18至0.46;电话:-0.44,95% CI -1.26至0.38;1项研究,N = 1801名成年人;中等确定性证据)。初级保健诊所由护士提供护理对儿童的BMI z评分影响可能很小或没有影响(MD -0.02,95% CI -0.16至0.12;1项研究,N = 52名儿童;极低确定性证据)两项研究报告了成本效益数据:一项研究支持邮件和标准护理而非电话咨询,另一项研究在两个干预组(医生和医生 - 营养师)中均以适度成本实现了体重减轻。一项关于共享护理的研究报告两组的不良反应相似。
我们几乎没有找到令人信服的证据表明所评估的任何干预措施对参与者的体重或BMI有临床重要影响。虽然三项研究的汇总结果表明,针对医疗保健专业人员的教育干预措施可能会使成年人的体重略有减轻,但这些结果的确定性较低。两项评估CDS工具(未汇总结果)以改善体重管理的试验表明,对超重或肥胖的成年人或儿童的体重或BMI变化影响很小或没有影响。所有其他评估干预措施的证据大多来自单项研究。主要结局(体重和BMI)的纳入证据的确定性从中等至极低不等。所有评估的干预措施都需要进一步研究,以确定它们作为改变医疗保健专业人员行为或护理组织方式的有效策略的优势和局限性。由于只有两项研究报告了成本,我们对所评估干预措施的成本效益了解甚少。